"Lipid A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Lipid A is the biologically active component of lipopolysaccharides. It shows strong endotoxic activity and exhibits immunogenic properties.
| Descriptor ID |
D008050
|
| MeSH Number(s) |
D09.698.718.450.500 D10.494.500 D23.050.161.616.525.500 D23.946.123.329.500.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Lipid A".
Below are MeSH descriptors whose meaning is more specific than "Lipid A".
This graph shows the total number of publications written about "Lipid A" by people in this website by year, and whether "Lipid A" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 1 | 2 |
| 2017 | 2 | 3 | 5 |
| 2018 | 3 | 1 | 4 |
| 2019 | 2 | 0 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Lipid A" by people in Profiles.
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SARS-CoV-2 spike protein binds to bacterial lipopolysaccharide and boosts proinflammatory activity. J Mol Cell Biol. 2020 10 12; 12(12):916-932.
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Safety of uSCIT-MPL-4: prevalence and risk factors of systemic reactions in real life. Immunotherapy. 2019 06; 11(9):783-794.
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First-in-human phase 1 dose-escalating trial of G305 in patients with advanced solid tumors expressing NY-ESO-1. Cancer Immunol Immunother. 2019 Jul; 68(7):1211-1222.
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Differences in Colistin-resistant Acinetobacter baumannii Clinical Isolates Between Patients With and Without Prior Colistin Treatment. Ann Lab Med. 2018 Nov; 38(6):545-554.
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Vaccination by microneedle patch with inactivated respiratory syncytial virus and monophosphoryl lipid A enhances the protective efficacy and diminishes inflammatory disease after challenge. PLoS One. 2018; 13(10):e0205071.
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The substrate-binding cap of the UDP-diacylglucosamine pyrophosphatase LpxH is highly flexible, enabling facile substrate binding and product release. J Biol Chem. 2018 05 25; 293(21):7969-7981.
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Monophosphoryl Lipid A-Adjuvanted Virosomes with Ni-Chelating Lipids for Attachment of Conserved Viral Proteins as Cross-Protective Influenza Vaccine. Biotechnol J. 2018 Apr; 13(4):e1700645.
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Dose Selection for an Adjuvanted Respiratory Syncytial Virus F Protein Vaccine for Older Adults Based on Humoral and Cellular Immune Responses. Clin Vaccine Immunol. 2017 Sep; 24(9).
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Sustained Immunogenicity of 2-dose Human Papillomavirus 16/18 AS04-adjuvanted Vaccine Schedules in Girls Aged 9-14 Years: A Randomized Trial. J Infect Dis. 2017 06 01; 215(11):1711-1719.
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Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults. PLoS Negl Trop Dis. 2017 05; 11(5):e0005574.