"Alkaptonuria" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An inborn error of amino acid metabolism resulting from a defect in the enzyme HOMOGENTISATE 1,2-DIOXYGENASE, an enzyme involved in the breakdown of PHENYLALANINE and TYROSINE. It is characterized by accumulation of HOMOGENTISIC ACID in the urine, OCHRONOSIS in various tissues, and ARTHRITIS.
| Descriptor ID |
D000474
|
| MeSH Number(s) |
C16.320.565.100.187 C18.452.648.100.187
|
| Concept/Terms |
Alkaptonuria- Alkaptonuria
- Homogentisic Acidura
- Alcaptonuria
- Alcaptonurias
- Homogentisic Acid Oxidase Deficiency
|
Below are MeSH descriptors whose meaning is more general than "Alkaptonuria".
Below are MeSH descriptors whose meaning is more specific than "Alkaptonuria".
This graph shows the total number of publications written about "Alkaptonuria" by people in this website by year, and whether "Alkaptonuria" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Alkaptonuria" by people in Profiles.
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A new integrated and interactive tool applicable to inborn errors of metabolism: Application to alkaptonuria. Comput Biol Med. 2018 12 01; 103:1-7.
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Histological and Ultrastructural Characterization of Alkaptonuric Tissues. Calcif Tissue Int. 2017 07; 101(1):50-64.