"Alkylating Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.
| Descriptor ID |
D000477
|
| MeSH Number(s) |
D27.505.519.124 D27.888.569.035
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Alkylating Agents".
Below are MeSH descriptors whose meaning is more specific than "Alkylating Agents".
This graph shows the total number of publications written about "Alkylating Agents" by people in this website by year, and whether "Alkylating Agents" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 2 | 0 | 2 |
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Below are the most recent publications written about "Alkylating Agents" by people in Profiles.
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Tube Shunt Revision With Excision of Fibrotic Capsule Using Mitomycin C With and Without Ologen-a Collagen Matrix Implant: A 3-Year Follow-up Study. J Glaucoma. 2019 11; 28(11):989-996.
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Use of busulfan in conditioning for allogeneic hematopoietic stem cell transplantation in adults: a survey by the Transplant Complications Working Party of the EBMT. Bone Marrow Transplant. 2019 12; 54(12):2013-2019.
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Trabeculectomy Outcomes After Glaucoma Drainage Device Surgery. J Glaucoma. 2018 02; 27(2):133-139.
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Trabeculectomy With Mitomycin-C: Outcomes and Risk Factors for Failure in Primary Angle-closure Glaucoma. J Glaucoma. 2018 02; 27(2):101-107.
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Endothelial cell changes after photorefractive keratectomy with graded usage of mitomycin C. Int Ophthalmol. 2018 Jun; 38(3):1211-1217.
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Long-term outcome after a treosulfan-based conditioning regimen for patients with acute myeloid leukemia: A report from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation. Cancer. 2017 Jul 15; 123(14):2671-2679.
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Induction of autophagy promotes the growth of early preneoplastic rat liver nodules. Oncotarget. 2016 Feb 02; 7(5):5788-99.
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[Behcet disease with cardiac and pulmonary manifestations]. Presse Med. 1998 Oct 31; 27(33):1674-6.
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[Anticancer chemotherapy. Prescription in the presence of renal insufficiency]. Nephrologie. 1995; 16(3):233-8.
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Higher-order structure in the 3'-terminal domain VI of the 23 S ribosomal RNAs from Escherichia coli and Bacillus stearothermophilus. J Mol Biol. 1984 Nov 15; 179(4):689-712.