"alpha-MSH" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 13-amino acid peptide derived from proteolytic cleavage of ADRENOCORTICOTROPIC HORMONE, the N-terminal segment of ACTH. ACTH (1-13) is amidated at the C-terminal to form ACTH (1-13)NH2 which in turn is acetylated to form alpha-MSH in the secretory granules. Alpha-MSH stimulates the synthesis and distribution of MELANIN in MELANOCYTES in mammals and MELANOPHORES in lower vertebrates.
Descriptor ID |
D000521
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MeSH Number(s) |
D06.472.699.327.935.179 D06.472.699.327.935.531.750.050 D06.472.699.631.525.600.179 D06.472.699.631.525.600.531.750.050 D12.644.400.400.935.179 D12.644.400.400.935.531.750.050 D12.644.400.460.050 D12.644.548.365.935.179 D12.644.548.365.935.531.750.050 D12.644.548.691.525.690.179 D12.644.548.691.525.690.531.750.050 D12.776.631.650.405.935.179 D12.776.631.650.405.935.531.750.050 D12.776.631.650.460.050
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Concept/Terms |
alpha-MSH- alpha-MSH
- alpha MSH
- alpha-Melanotropin
- alpha Melanotropin
- Acetylated ACTH (1-13)NH2
- alpha-Melanocyte-Stimulating Hormone
- Hormone, alpha-Melanocyte-Stimulating
- alpha Melanocyte Stimulating Hormone
- MSH, alpha
ACTH (1-13)NH2- ACTH (1-13)NH2
- (Desacetyl)alpha-MSH
- DE-alpha-MSH
- MSH, (Desacetyl)alpha-
- Des-Acetyl MSH
- MSH, Des-Acetyl
- Desacetyl alpha-MSH
- Desacetyl alpha MSH
- alpha-MSH, Desacetyl
- Desacetyl alpha-Melanocyte-Stimulating Hormone
- Desacetyl alpha Melanocyte Stimulating Hormone
- Hormone, Desacetyl alpha-Melanocyte-Stimulating
- alpha-Melanocyte-Stimulating Hormone, Desacetyl
- (Des-Acetyl)-alpha-MSH
- Adrenocorticotropin (1-13)NH2
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Below are MeSH descriptors whose meaning is more general than "alpha-MSH".
Below are MeSH descriptors whose meaning is more specific than "alpha-MSH".
This graph shows the total number of publications written about "alpha-MSH" by people in this website by year, and whether "alpha-MSH" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2003 | 1 | 0 | 1 |
2007 | 0 | 1 | 1 |
2017 | 1 | 1 | 2 |
2018 | 1 | 1 | 2 |
2019 | 0 | 2 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "alpha-MSH" by people in Profiles.
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Alpha-MSH Targeted Liposomal Nanoparticle for Imaging in Inflammatory Bowel Disease (IBD). Curr Pharm Des. 2020; 26(31):3840-3846.
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Hypothesis: does adrenalitis caused by immune checkpoint-inhibitors put melanoma patients at an elevated risk for recurrence? J Immunother Cancer. 2019 07 04; 7(1):166.
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What's New in Pigmentary Disorders. Dermatol Clin. 2019 Apr; 37(2):175-181.
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Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment. J Clin Endocrinol Metab. 2018 07 01; 103(7):2601-2612.
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Altered levels of a-melanocyte stimulating hormone in cerebrospinal fluid and plasma of patients with traumatic brain injury. Brain Res. 2018 10 01; 1696:22-30.
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Soyasaponin Ag inhibits a-MSH-induced melanogenesis in B16F10 melanoma cells via the downregulation of TRP-2. Int J Mol Med. 2017 Sep; 40(3):631-636.
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Paternal hyperglycemia in rats exacerbates the development of obesity in offspring. J Endocrinol. 2017 Aug; 234(2):175-186.
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Melanocortin activation of nucleus of the solitary tract avoids anorectic tachyphylaxis and induces prolonged weight loss. Am J Physiol Endocrinol Metab. 2007 Jul; 293(1):E252-8.
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ACTH and alpha-MSH inhibit leptin expression and secretion in 3T3-L1 adipocytes: model for a central-peripheral melanocortin-leptin pathway. Mol Cell Endocrinol. 2003 Feb 28; 200(1-2):99-109.