Colorectal Neoplasms, Hereditary Nonpolyposis
"Colorectal Neoplasms, Hereditary Nonpolyposis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of autosomal-dominant inherited diseases in which COLON CANCER arises in discrete adenomas. Unlike FAMILIAL POLYPOSIS COLI with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. HNPCC has been associated with germline mutations in mismatch repair (MMR) genes. It has been subdivided into Lynch syndrome I or site-specific colonic cancer, and LYNCH SYNDROME II which includes extracolonic cancer.
| Descriptor ID |
D003123
|
| MeSH Number(s) |
C04.588.274.476.411.307.190 C04.700.250 C06.301.371.411.307.190 C06.405.249.411.307.190 C06.405.469.158.356.190 C06.405.469.491.307.190 C16.320.700.250 C18.452.284.255
|
| Concept/Terms |
Hereditary Nonpolyposis Colorectal Cancer- Hereditary Nonpolyposis Colorectal Cancer
- Colorectal Cancer Hereditary Nonpolyposis
- Lynch Syndrome I
- Lynch Cancer Family Syndrome I
- Lynch Syndrome
- Syndrome, Lynch
- Colon Cancer, Familial Nonpolyposis
- Hereditary Nonpolyposis Colon Cancer
|
Below are MeSH descriptors whose meaning is more general than "Colorectal Neoplasms, Hereditary Nonpolyposis".
- Diseases [C]
- Neoplasms [C04]
- Neoplasms by Site [C04.588]
- Digestive System Neoplasms [C04.588.274]
- Gastrointestinal Neoplasms [C04.588.274.476]
- Intestinal Neoplasms [C04.588.274.476.411]
- Colorectal Neoplasms [C04.588.274.476.411.307]
- Colorectal Neoplasms, Hereditary Nonpolyposis [C04.588.274.476.411.307.190]
- Neoplastic Syndromes, Hereditary [C04.700]
- Colorectal Neoplasms, Hereditary Nonpolyposis [C04.700.250]
- Digestive System Diseases [C06]
- Digestive System Neoplasms [C06.301]
- Gastrointestinal Neoplasms [C06.301.371]
- Intestinal Neoplasms [C06.301.371.411]
- Colorectal Neoplasms [C06.301.371.411.307]
- Colorectal Neoplasms, Hereditary Nonpolyposis [C06.301.371.411.307.190]
- Gastrointestinal Diseases [C06.405]
- Gastrointestinal Neoplasms [C06.405.249]
- Intestinal Neoplasms [C06.405.249.411]
- Colorectal Neoplasms [C06.405.249.411.307]
- Colorectal Neoplasms, Hereditary Nonpolyposis [C06.405.249.411.307.190]
- Intestinal Diseases [C06.405.469]
- Colonic Diseases [C06.405.469.158]
- Colorectal Neoplasms [C06.405.469.158.356]
- Colorectal Neoplasms, Hereditary Nonpolyposis [C06.405.469.158.356.190]
- Intestinal Neoplasms [C06.405.469.491]
- Colorectal Neoplasms [C06.405.469.491.307]
- Colorectal Neoplasms, Hereditary Nonpolyposis [C06.405.469.491.307.190]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
- Neoplastic Syndromes, Hereditary [C16.320.700]
- Colorectal Neoplasms, Hereditary Nonpolyposis [C16.320.700.250]
- Nutritional and Metabolic Diseases [C18]
- Metabolic Diseases [C18.452]
- DNA Repair-Deficiency Disorders [C18.452.284]
- Colorectal Neoplasms, Hereditary Nonpolyposis [C18.452.284.255]
Below are MeSH descriptors whose meaning is more specific than "Colorectal Neoplasms, Hereditary Nonpolyposis".
This graph shows the total number of publications written about "Colorectal Neoplasms, Hereditary Nonpolyposis" by people in this website by year, and whether "Colorectal Neoplasms, Hereditary Nonpolyposis" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2017 | 3 | 1 | 4 |
| 2018 | 4 | 1 | 5 |
| 2021 | 2 | 0 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Colorectal Neoplasms, Hereditary Nonpolyposis" by people in Profiles.
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Deficient DNA mismatch repair and persistence of SARS-CoV-2 RNA shedding: a case report of hereditary nonpolyposis colorectal cancer with COVID-19 infection. BMC Infect Dis. 2021 Aug 21; 21(1):854.
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COVID-19 Disruptions to Endoscopic Surveillance in Lynch Syndrome. Cancer Prev Res (Phila). 2021 05; 14(5):521-526.
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Exploring the real-world effect of the SARS-CoV-2 pandemic on the molecular diagnostics for cancer patients and high-risk individuals. Expert Rev Mol Diagn. 2021 01; 21(1):101-107.
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Management strategies for the colonoscopic surveillance of people with Lynch syndrome during the COVID-19 pandemic. Gut. 2021 03; 70(3):624-626.
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Germline variation in the oxidative DNA repair genes NUDT1 and OGG1 is not associated with hereditary colorectal cancer or polyposis. Hum Mutat. 2018 09; 39(9):1214-1225.
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Cancer prevention by aspirin in children with Constitutional Mismatch Repair Deficiency (CMMRD). Eur J Hum Genet. 2018 10; 26(10):1417-1423.
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Germline mutations in the spindle assembly checkpoint genes BUB1 and BUB3 are infrequent in familial colorectal cancer and polyposis. Mol Cancer. 2018 02 15; 17(1):23.
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Imaging findings of hereditary renal tumors, a review of what the radiologist should know. Eur J Radiol. 2018 Apr; 101:8-16.
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Which Lynch syndrome screening programs could be implemented in the "real world"? A systematic review of economic evaluations. Genet Med. 2018 10; 20(10):1131-1144.
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Poor performance of clinical prediction models: the harm of commonly applied methods. J Clin Epidemiol. 2018 06; 98:133-143.