"Caffeine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.
| Descriptor ID |
D002110
|
| MeSH Number(s) |
D03.132.960.175 D03.633.100.759.758.824.175
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Caffeine".
Below are MeSH descriptors whose meaning is more specific than "Caffeine".
This graph shows the total number of publications written about "Caffeine" by people in this website by year, and whether "Caffeine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 6 | 1 | 7 |
| 2018 | 10 | 8 | 18 |
| 2019 | 5 | 3 | 8 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Caffeine" by people in Profiles.
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Possible Beneficial Actions of Caffeine in SARS-CoV-2. Int J Mol Sci. 2021 May 22; 22(11).
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Energy drinks and medical students: Bad drinking during COVID-19 quarantine. Appl Nurs Res. 2021 06; 59:151429.
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Simultaneous Determination of Paracetamol, Propyphenazone and Caffeine in Presence of Paracetamol Impurities Using Dual-Mode Gradient HPLC and TLC Densitometry Methods. J Chromatogr Sci. 2021 Jan 14; 59(2):140-147.
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Rediscovery of Caffeine: An Excellent Drug for Improving Patient Outcomes while Fighting WARS. Curr Med Chem. 2021; 28(27):5449-5462.
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The importance of early use of beta blockers and gastric decontamination in caffeine overdose: A case report. Aust Crit Care. 2021 07; 34(4):395-400.
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Caffeine and caffeine-containing pharmaceuticals as promising inhibitors for 3-chymotrypsin-like protease of SARS-CoV-2. J Biomol Struct Dyn. 2022 Mar; 40(5):2113-2120.
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Can pentoxifylline and similar xanthine derivatives find a niche in COVID-19 therapeutic strategies? A ray of hope in the midst of the pandemic. Eur J Pharmacol. 2020 Nov 15; 887:173561.
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Caffeine, Type of Coffee, and Risk of Ovarian Cancer: A Dose-Response Meta-Analysis of Prospective Studies. J Clin Endocrinol Metab. 2019 11 01; 104(11):5349-5359.
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Caffeine and myocardial perfusion: a clinical perspective. Eur Heart J Cardiovasc Imaging. 2019 07 01; 20(7):763-764.
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Morningness-eveningness and caffeine consumption: A largescale path-analysis study. Chronobiol Int. 2019 09; 36(9):1301-1309.