"Drug Antagonism" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Phenomena and pharmaceutics of compounds that inhibit the function of agonists (DRUG AGONISM) and inverse agonists (DRUG INVERSE AGONISM) for a specific receptor. On their own, antagonists produce no effect by themselves to a receptor, and are said to have neither intrinsic activity nor efficacy.
| Descriptor ID |
D004336
|
| MeSH Number(s) |
G07.690.773.968.310
|
| Concept/Terms |
Drug Antagonism- Drug Antagonism
- Antagonism, Drug
- Antagonisms, Drug
- Drug Antagonisms
|
Below are MeSH descriptors whose meaning is more general than "Drug Antagonism".
Below are MeSH descriptors whose meaning is more specific than "Drug Antagonism".
This graph shows the total number of publications written about "Drug Antagonism" by people in this website by year, and whether "Drug Antagonism" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 2 | 2 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Drug Antagonism" by people in Profiles.
-
Hydroxychloroquine (HCQ) decreases the benefit of anti-PD-1 immune checkpoint blockade in tumor immunotherapy. PLoS One. 2021; 16(6):e0251731.
-
In vitro evaluation of antiviral activity of single and combined repurposable drugs against SARS-CoV-2. Antiviral Res. 2020 09; 181:104878.
-
Synergistic Effects of Plant Derivatives and Conventional Chemotherapeutic Agents: An Update on the Cancer Perspective. Medicina (Kaunas). 2019 Apr 17; 55(4).
-
Loss of Control of HIV Viremia With OTC Weight-Loss Drugs: A Call for Caution? Obesity (Silver Spring). 2018 08; 26(8):1251-1252.
-
Activin A inhibits organization of sarcomeric proteins in cardiomyocytes induced by leukemia inhibitory factor. J Mol Cell Cardiol. 2006 Oct; 41(4):689-97.
-
Tumor necrosis factor-alpha protects synovial cells from nitric oxide induced apoptosis through phosphoinositide 3-kinase Akt signal transduction. J Rheumatol. 2006 Jun; 33(6):1061-8.