"Diphosphonates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.
| Descriptor ID |
D004164
|
| MeSH Number(s) |
D02.705.429.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Diphosphonates".
Below are MeSH descriptors whose meaning is more specific than "Diphosphonates".
This graph shows the total number of publications written about "Diphosphonates" by people in this website by year, and whether "Diphosphonates" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 2 | 0 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 10 | 11 | 21 |
| 2018 | 11 | 5 | 16 |
| 2019 | 5 | 1 | 6 |
| 2020 | 3 | 1 | 4 |
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Below are the most recent publications written about "Diphosphonates" by people in Profiles.
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NMPylation and de-NMPylation of SARS-CoV-2 nsp9 by the NiRAN domain. Nucleic Acids Res. 2021 09 07; 49(15):8822-8835.
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The Use of Oral Amino-Bisphosphonates and Coronavirus Disease 2019 (COVID-19) Outcomes. J Bone Miner Res. 2021 11; 36(11):2177-2183.
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Risk of Invasive Fungal Infections and Osteonecrosis of Jaw in Patients Exposed to Current Therapeutic Drugs for COVID-19. J Coll Physicians Surg Pak. 2021 Jul; 31(7):150-151.
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Management of Primary Hyperparathyroidism With Severe Hypercalcemia During the COVID-19 Pandemic. Clin Ther. 2021 04; 43(4):711-719.
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MRONJ and COVID-19 caution. Br Dent J. 2021 01; 230(2):59-60.
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Osteoporosis Management Strategies in the COVID-19 Pandemic. South Med J. 2020 12; 113(12):612-613.
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Controversies in the use of new bone-modifying therapies in multiple myeloma. Br J Haematol. 2021 Jun; 193(6):1034-1043.
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Gorham-Stout Syndrome: A Phantom Bone Disease Treated With Bisphosphonates. J Clin Rheumatol. 2020 Aug; 26(5):e135-e136.
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Boning up: amino-bisphophonates as immunostimulants and endosomal disruptors of dendritic cell in SARS-CoV-2 infection. J Transl Med. 2020 06 29; 18(1):261.
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Risk and management of patients with mastocytosis and MCAS in the SARS-CoV-2 (COVID-19) pandemic: Expert opinions. J Allergy Clin Immunol. 2020 08; 146(2):300-306.