"Leucine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An essential branched-chain amino acid important for hemoglobin formation.
| Descriptor ID |
D007930
|
| MeSH Number(s) |
D12.125.070.637 D12.125.142.441
|
| Concept/Terms |
Leucine- Leucine
- L-Leucine
- Leucine, L-Isomer
- L-Isomer Leucine
- Leucine, L Isomer
|
Below are MeSH descriptors whose meaning is more general than "Leucine".
Below are MeSH descriptors whose meaning is more specific than "Leucine".
This graph shows the total number of publications written about "Leucine" by people in this website by year, and whether "Leucine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 4 | 5 |
| 2018 | 1 | 12 | 13 |
| 2019 | 1 | 2 | 3 |
| 2020 | 0 | 2 | 2 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Leucine" by people in Profiles.
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Supervised Molecular Dynamics (SuMD) Insights into the mechanism of action of SARS-CoV-2 main protease inhibitor PF-07321332. J Enzyme Inhib Med Chem. 2021 Dec; 36(1):1646-1650.
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Challenges of short substrate analogues as SARS-CoV-2 main protease inhibitors. Bioorg Med Chem Lett. 2021 10 15; 50:128333.
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The interaction of the severe acute respiratory syndrome coronavirus 2 spike protein with drug-inhibited angiotensin converting enzyme 2 studied by molecular dynamics simulation. J Hypertens. 2021 08 01; 39(8):1705-1716.
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Characterization of the Modulatory Effect of Hydroxychloroquine on ACE2 Activity: New Insights in relation to COVID-19. Biomed Res Int. 2021; 2021:6614000.
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Mechanism of Ligand Recognition by Human ACE2 Receptor. J Phys Chem Lett. 2021 May 27; 12(20):4814-4822.
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Efficacy of GC-376 against SARS-CoV-2 virus infection in the K18 hACE2 transgenic mouse model. Sci Rep. 2021 05 05; 11(1):9609.
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The race for antiviral drugs to beat COVID - and the next pandemic. Nature. 2021 04; 592(7854):340-343.
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Is PF-00835231 a Pan-SARS-CoV-2 Mpro Inhibitor? A Comparative Study. Molecules. 2021 Mar 17; 26(6).
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Boceprevir, Calpain Inhibitors II and XII, and GC-376 Have Broad-Spectrum Antiviral Activity against Coronaviruses. ACS Infect Dis. 2021 03 12; 7(3):586-597.
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Structural basis for the inhibition of the SARS-CoV-2 main protease by the anti-HCV drug narlaprevir. Signal Transduct Target Ther. 2021 02 04; 6(1):51.