"Thioctic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
| Descriptor ID |
D008063
|
| MeSH Number(s) |
D02.241.803 D02.886.778.827 D08.211.906 D10.251.941
|
| Concept/Terms |
Thioctic Acid- Thioctic Acid
- alpha-Lipoic Acid
- Acid, alpha-Lipoic
- alpha Lipoic Acid
- Lipoic Acid
|
Below are MeSH descriptors whose meaning is more general than "Thioctic Acid".
Below are MeSH descriptors whose meaning is more specific than "Thioctic Acid".
This graph shows the total number of publications written about "Thioctic Acid" by people in this website by year, and whether "Thioctic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2017 | 4 | 0 | 4 |
| 2018 | 5 | 0 | 5 |
| 2019 | 2 | 0 | 2 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Thioctic Acid" by people in Profiles.
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Mechanics Insights of Alpha-Lipoic Acid against Cardiovascular Diseases during COVID-19 Infection. Int J Mol Sci. 2021 Jul 26; 22(15).
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Potential roles of mitochondrial cofactors in the adjuvant mitigation of proinflammatory acute infections, as in the case of sepsis and COVID-19 pneumonia. Inflamm Res. 2021 Feb; 70(2):159-170.
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Alpha-lipoic acid may protect patients with diabetes against COVID-19 infection. Med Hypotheses. 2020 Oct; 143:110185.
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G6PD deficiency in the COVID-19 pandemic: Ghost within Ghost. Hematol Oncol Stem Cell Ther. 2021 Mar; 14(1):84-85.
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N2L, a novel lipoic acid-niacin dimer protects HT22 cells against ß-amyloid peptide-induced damage through attenuating apoptosis. Metab Brain Dis. 2019 12; 34(6):1761-1770.
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a-Lipoic Acid Reduces Iron-induced Toxicity and Oxidative Stress in a Model of Iron Overload. Int J Mol Sci. 2019 Jan 31; 20(3).
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Prevention of Bortezomib-Related Peripheral Neuropathy With Docosahexaenoic Acid and a-Lipoic Acid in Patients With Multiple Myeloma: Preliminary Data. Integr Cancer Ther. 2018 12; 17(4):1115-1124.
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The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials. Metabolism. 2018 10; 87:56-69.
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Ex-vivo absorption study of lysine R-lipoate salt, a new pharmaceutical form of R-ALA. Eur J Pharm Sci. 2018 Jun 15; 118:200-207.
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Early alpha-lipoic acid therapy protects from degeneration of the inner retinal layers and vision loss in an experimental autoimmune encephalomyelitis-optic neuritis model. J Neuroinflammation. 2018 Mar 07; 15(1):71.