"Dimethyl Sulfoxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
| Descriptor ID |
D004121
|
| MeSH Number(s) |
D02.886.640.150
|
| Concept/Terms |
Dimethyl Sulfoxide- Dimethyl Sulfoxide
- Sulfoxide, Dimethyl
- Dimethylsulphinyl
- Sulfinylbis(methane)
- Dimethyl Sulphoxide
- Sulphoxide, Dimethyl
- Dimethylsulfoxide
- Dimethylsulphoxide
- DMSO
|
Below are MeSH descriptors whose meaning is more general than "Dimethyl Sulfoxide".
Below are MeSH descriptors whose meaning is more specific than "Dimethyl Sulfoxide".
This graph shows the total number of publications written about "Dimethyl Sulfoxide" by people in this website by year, and whether "Dimethyl Sulfoxide" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 1 | 2 | 3 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Dimethyl Sulfoxide" by people in Profiles.
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Evaluating Stability and Activity of SARS-CoV-2 PLpro for High-throughput Screening of Inhibitors. Mol Biotechnol. 2022 Jan; 64(1):1-8.
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Dimethyl sulfoxide reduces the stability but enhances catalytic activity of the main SARS-CoV-2 protease 3CLpro. FASEB J. 2021 08; 35(8):e21774.
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The Inhibitory Effects of Plant Derivate Polyphenols on the Main Protease of SARS Coronavirus 2 and Their Structure-Activity Relationship. Molecules. 2021 Mar 30; 26(7).
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Zinc Iodide in combination with Dimethyl Sulfoxide for treatment of SARS-CoV-2 and other viral infections. Med Hypotheses. 2020 Oct; 143:109866.
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High-throughput quantification of the effect of DMSO on the viability of lung and breast cancer cells using an easy-to-use spectrophotometric trypan blue-based assay. Histochem Cell Biol. 2019 Jul; 152(1):75-84.
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Comparison of time to engraftment between autologous patients receiving washed versus non-washed cryopreserved peripheral blood stem cell products. Leuk Lymphoma. 2018 12; 59(12):2829-2835.
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Investigation of Anesthetic-Protein Interactions by a Thermodynamic Approach. Methods Enzymol. 2018; 603:103-113.
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DMSO as a mobile phase additive enhances detection of ubiquitination sites by nano-LC-ESI-MS/MS. J Mass Spectrom. 2018 Feb; 53(2):183-187.
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Onyx embolization prior to stereotactic radiosurgery for brain arteriovenous malformations: a single-center treatment algorithm. J Neurointerv Surg. 2018 Mar; 10(3):258-267.
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A prospective randomized controlled multicentre trial comparing intravesical DMSO and chondroïtin sulphate 2% for painful bladder syndrome/interstitial cystitis. Int Braz J Urol. 2017 Jan-Feb; 43(1):134-141.