"Mevalonic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dihydroxy monocarboxylic acid and precursor in the biosynthetic pathway known as the mevalonate pathway, which produces terpenes and steroids that are vital for diverse cellular functions.
| Descriptor ID |
D008798
|
| MeSH Number(s) |
D02.241.511.579
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Mevalonic Acid".
Below are MeSH descriptors whose meaning is more specific than "Mevalonic Acid".
This graph shows the total number of publications written about "Mevalonic Acid" by people in this website by year, and whether "Mevalonic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2017 | 3 | 0 | 3 |
| 2018 | 2 | 0 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mevalonic Acid" by people in Profiles.
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Lipid homeostasis and mevalonate pathway in COVID-19: Basic concepts and potential therapeutic targets. Prog Lipid Res. 2021 04; 82:101099.
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Dysregulation of the mevalonate pathway during SARS-CoV-2 infection: An in silico study. J Med Virol. 2021 04; 93(4):2396-2405.
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Mevalonate pathway, selenoproteins, redox balance, immune system, Covid-19: Reasoning about connections. Med Hypotheses. 2020 Nov; 144:110128.
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Complete biosynthesis of cannabinoids and their unnatural analogues in yeast. Nature. 2019 03; 567(7746):123-126.
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Role of statins and mevalonate pathway on impaired HDAC2 activity induced by oxidative stress in human airway epithelial cells. Eur J Pharmacol. 2018 Aug 05; 832:114-119.
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Metabolic Induction of Trained Immunity through the Mevalonate Pathway. Cell. 2018 01 11; 172(1-2):135-146.e9.
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Expression of key enzymes in the mevalonate pathway are altered in monocrotaline-induced pulmonary arterial hypertension in rats. Mol Med Rep. 2017 Dec; 16(6):9593-9600.
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Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells. Sci Rep. 2017 03 27; 7:44841.
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Editorial: New Insights into a Classical Pathway: Key Roles of the Mevalonate Cascade in Different Diseases (Part II). Curr Mol Pharmacol. 2017; 10(2):74-76.
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Sesquiterpene farnesol inhibits recycling of the C55 lipid carrier of the murein monomer precursor contributing to increased susceptibility to beta-lactams in methicillin-resistant Staphylococcus aureus. J Antimicrob Chemother. 2007 Mar; 59(3):425-32.