"Ethacrynic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
| Descriptor ID |
D004976
|
| MeSH Number(s) |
D02.241.081.018.386.682.300 D02.241.511.316.682.200
|
| Concept/Terms |
Ethacrynic Acid- Ethacrynic Acid
- Acid, Ethacrynic
- Etacrynic Acid
- Acid, Etacrynic
- Ethacrinic Acid
- Acid, Ethacrinic
|
Below are MeSH descriptors whose meaning is more general than "Ethacrynic Acid".
Below are MeSH descriptors whose meaning is more specific than "Ethacrynic Acid".
This graph shows the total number of publications written about "Ethacrynic Acid" by people in this website by year, and whether "Ethacrynic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ethacrynic Acid" by people in Profiles.
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Systematic Search for SARS-CoV-2 Main Protease Inhibitors for Drug Repurposing: Ethacrynic Acid as a Potential Drug. Viruses. 2021 Jan 13; 13(1).
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Influence of glutathione-S-transferase (GST) inhibition on lung epithelial cell injury: role of oxidative stress and metabolism. Am J Physiol Lung Cell Mol Physiol. 2015 Jun 15; 308(12):L1274-85.
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A new lead for nonpeptidic active-site-directed inhibitors of the severe acute respiratory syndrome coronavirus main protease discovered by a combination of screening and docking methods. J Med Chem. 2005 Nov 03; 48(22):6832-42.