"Oncolytic Viruses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tumor-selective, replication competent VIRUSES that have antineoplastic effects. This is achieved by producing cytotoxicity-enhancing proteins and/or eliciting an antitumor immune response. They are genetically engineered so that they can replicate in CANCER cells but not in normal cells, and are used in ONCOLYTIC VIROTHERAPY.
| Descriptor ID |
D050504
|
| MeSH Number(s) |
B04.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Oncolytic Viruses".
Below are MeSH descriptors whose meaning is more specific than "Oncolytic Viruses".
This graph shows the total number of publications written about "Oncolytic Viruses" by people in this website by year, and whether "Oncolytic Viruses" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 3 | 4 |
| 2018 | 7 | 0 | 7 |
| 2019 | 2 | 1 | 3 |
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Below are the most recent publications written about "Oncolytic Viruses" by people in Profiles.
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Oncolytic viral immunotherapy in the time of COVID-19. Cytokine Growth Factor Rev. 2020 12; 56:1-3.
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Xenoantigen-Dependent Complement-Mediated Neutralization of Lymphocytic Choriomeningitis Virus Glycoprotein-Pseudotyped Vesicular Stomatitis Virus in Human Serum. J Virol. 2019 09 15; 93(18).
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A clinical trial investigating biodistribution and shedding of an oncolytic virus. EBioMedicine. 2019 09; 47:4-5.
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Bibliometric analysis of oncolytic virus research, 2000 to 2018. Medicine (Baltimore). 2019 Aug; 98(35):e16817.
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A Novel Chimeric Oncolytic Virus Vector for Improved Safety and Efficacy as a Platform for the Treatment of Hepatocellular Carcinoma. J Virol. 2018 12 01; 92(23).
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Heparan Sulfate Binding Coxsackievirus B3 Strain PD: A Novel Avirulent Oncolytic Agent Against Human Colorectal Carcinoma. Hum Gene Ther. 2018 11; 29(11):1301-1314.
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Cancer-killing viruses show promise - and draw billion-dollar investment. Nature. 2018 05; 557(7704):150-151.
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The Oncolytic Virus VSV-GP Is Effective against Malignant Melanoma. Viruses. 2018 03 02; 10(3).
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Oncotargeting by Vesicular Stomatitis Virus (VSV): Advances in Cancer Therapy. Viruses. 2018 02 23; 10(2).
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Targeted BiTE Expression by an Oncolytic Vector Augments Therapeutic Efficacy Against Solid Tumors. Clin Cancer Res. 2018 05 01; 24(9):2128-2137.