Insulin-Like Growth Factor II
"Insulin-Like Growth Factor II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A well-characterized neutral peptide believed to be secreted by the LIVER and to circulate in the BLOOD. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not absolute, dependence on SOMATOTROPIN. It is believed to be a major fetal growth factor in contrast to INSULIN-LIKE GROWTH FACTOR I, which is a major growth factor in adults.
Descriptor ID |
D007335
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MeSH Number(s) |
D12.644.276.937.420 D12.776.124.862.425 D12.776.467.937.420 D23.529.937.420
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Concept/Terms |
Insulin-Like Growth Factor II- Insulin-Like Growth Factor II
- IGF-II
- Insulin Like Growth Factor II
- Insulin-Like Somatomedin Peptide II
- Insulin Like Somatomedin Peptide II
- Multiplication-Stimulating Factor
- Factor, Multiplication-Stimulating
- Multiplication Stimulating Factor
- Somatomedin A
- Somatomedin MSA
- IGF-2
- Multiplication-Stimulating Activity
- Multiplication Stimulating Activity
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Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor II".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor II".
This graph shows the total number of publications written about "Insulin-Like Growth Factor II" by people in this website by year, and whether "Insulin-Like Growth Factor II" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 1 | 0 | 1 |
2017 | 3 | 3 | 6 |
2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Insulin-Like Growth Factor II" by people in Profiles.
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Direct repression of IGF2 is implicated in the anti-angiogenic function of microRNA-210 in human retinal endothelial cells. Angiogenesis. 2018 05; 21(2):313-323.
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A Hypoglycemia-inducing Giant Borderline Phyllodes Tumor Secreting High-molecular-weight Insulin-Like Growth Factor II: Immunohistochemistry and a Western Blot Analysis. Intern Med. 2018 Jan 15; 57(2):237-241.
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Effects of Liraglutide on Weight Loss, Fat Distribution, and ß-Cell Function in Obese Subjects With Prediabetes or Early Type 2 Diabetes. Diabetes Care. 2017 11; 40(11):1556-1564.
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Methylation status of IGF2 DMR and LINE1 in leukocyte DNA provides distinct clinicopathological features of gastric cancer patients. Clin Exp Med. 2018 May; 18(2):215-220.
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[Effects of obesity on global genome DNA methylation and gene imprinting in mouse spermatozoa]. Zhonghua Nan Ke Xue. 2017 Jun; 23(6):488-496.
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Fateful imprints. Science. 2017 Jan 13; 355(6321):122-125.
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Prevalence of Prediabetes Risk in Offspring Born to Mothers with Hyperandrogenism. EBioMedicine. 2017 Feb; 16:275-283.
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Low insulin-like growth factor-II levels predict weight gain in normal weight subjects with type 2 diabetes. Am J Med. 2006 Feb; 119(2):167.e9-15.