"Transglutaminases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Transglutaminases catalyze cross-linking of proteins at a GLUTAMINE in one chain with LYSINE in another chain. They include keratinocyte transglutaminase (TGM1 or TGK), tissue transglutaminase (TGM2 or TGC), plasma transglutaminase involved with coagulation (FACTOR XIII and FACTOR XIIIa), hair follicle transglutaminase, and prostate transglutaminase. Although structures differ, they share an active site (YGQCW) and strict CALCIUM dependence.
Descriptor ID |
D011503
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MeSH Number(s) |
D08.811.913.050.200.800
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Concept/Terms |
Transglutaminases- Transglutaminases
- Protein-Glutamine gamma-Glutamyltransferases
- Protein Glutamine gamma Glutamyltransferases
- gamma-Glutamyltransferases, Protein-Glutamine
- Glutaminyl-Peptide Gamma-Glutamyltransferases
- Gamma-Glutamyltransferases, Glutaminyl-Peptide
- Glutaminyl Peptide Gamma Glutamyltransferases
|
Below are MeSH descriptors whose meaning is more general than "Transglutaminases".
Below are MeSH descriptors whose meaning is more specific than "Transglutaminases".
This graph shows the total number of publications written about "Transglutaminases" by people in this website by year, and whether "Transglutaminases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 |
1999 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
2014 | 0 | 1 | 1 |
2016 | 2 | 0 | 2 |
2017 | 5 | 6 | 11 |
2018 | 7 | 4 | 11 |
2019 | 4 | 0 | 4 |
2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transglutaminases" by people in Profiles.
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Unique autoantibody prevalence in long-term recovered SARS-CoV-2-infected individuals. J Autoimmun. 2021 08; 122:102682.
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Transglutaminase 2 Regulates Innate Immunity by Modulating the STING/TBK1/IRF3 Axis. J Immunol. 2021 05 15; 206(10):2420-2429.
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ESPGHAN 'biopsy-sparing' guidelines for celiac disease in children with low antitransglutaminase during COVID-19. Eur J Gastroenterol Hepatol. 2020 12; 32(12):1523-1526.
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A negative fallout of COVID-19 lockdown in Italy: Life-threatening delay in the diagnosis of celiac disease. Dig Liver Dis. 2020 10; 52(10):1092-1093.
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Measuring too much or too little in adult coeliac disease. J Clin Pathol. 2019 05; 72(5):341-342.
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HLA-DQ2 homozygosis increases tTGA levels at diagnosis but does not influence the clinical phenotype of coeliac disease: A multicentre study. Int J Immunogenet. 2019 Apr; 46(2):74-81.
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Transglutaminase type 2 in the regulation of proteostasis. Biol Chem. 2019 01 28; 400(2):125-140.
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Role of anti-tissue transglutaminase IgA+IgG antibodies in detection of potential celiac disease in patients with type 1 diabetes. Indian J Med Res. 2019 Jan; 149(1):18-25.
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Transglutaminase Type 2 Regulates ER-Mitochondria Contact Sites by Interacting with GRP75. Cell Rep. 2018 12 26; 25(13):3573-3581.e4.
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Identification of autoimmune type 1 diabetes and multiple organ-specific autoantibodies in adult-onset non-insulin-requiring diabetes in China: A population-based multicentre nationwide survey. Diabetes Obes Metab. 2019 04; 21(4):893-902.