"Manganese" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
| Descriptor ID |
D008345
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| MeSH Number(s) |
D01.268.556.484 D01.268.956.374 D01.552.544.484
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Manganese".
Below are MeSH descriptors whose meaning is more specific than "Manganese".
This graph shows the total number of publications written about "Manganese" by people in this website by year, and whether "Manganese" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 1 | 2 |
| 2017 | 19 | 7 | 26 |
| 2018 | 11 | 3 | 14 |
| 2019 | 4 | 1 | 5 |
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Below are the most recent publications written about "Manganese" by people in Profiles.
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NMPylation and de-NMPylation of SARS-CoV-2 nsp9 by the NiRAN domain. Nucleic Acids Res. 2021 09 07; 49(15):8822-8835.
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Mn2+ coordinates Cap-0-RNA to align substrates for efficient 2'-O-methyl transfer by SARS-CoV-2 nsp16. Sci Signal. 2021 06 29; 14(689).
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Metal-Bound Methisazone; Novel Drugs Targeting Prophylaxis and Treatment of SARS-CoV-2, a Molecular Docking Study. Int J Mol Sci. 2021 Mar 15; 22(6).
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Coronavirus replication-transcription complex: Vital and selective NMPylation of a conserved site in nsp9 by the NiRAN-RdRp subunit. Proc Natl Acad Sci U S A. 2021 02 09; 118(6).
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The role of poly(ADP-ribose) polymerases in manganese exposed Caenorhabditis elegans. J Trace Elem Med Biol. 2020 Jan; 57:21-27.
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Class Id ribonucleotide reductase utilizes a Mn2(IV,III) cofactor and undergoes large conformational changes on metal loading. J Biol Inorg Chem. 2019 09; 24(6):863-877.
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Reproducibility of essential elements chromium, manganese, iron, zinc and selenium in spot samples, first-morning voids and 24-h collections from healthy adult men. Br J Nutr. 2019 08 14; 122(3):343-351.
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Pivotal role of cAMP-PKA-CREB signaling pathway in manganese-induced neurotoxicity in PC12 cells. Environ Toxicol. 2019 Sep; 34(9):1052-1062.
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Performance and microbial community profiles in pilot-scale biofilter for ammonia, iron and manganese removal at different dissolved oxygen concentrations. World J Microbiol Biotechnol. 2019 Feb 19; 35(3):43.
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Appraising spatial variations of As, Fe, Mn and NO3 contaminations associated health risks of drinking water from Surma basin, Bangladesh. Chemosphere. 2019 Mar; 218:726-740.