Receptors, Tumor Necrosis Factor, Member 14
"Receptors, Tumor Necrosis Factor, Member 14" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A novel member of the tumor-necrosis factor receptor family that can also mediate HERPES SIMPLEX VIRUS TYPE 1 entry into cells. It has specificity for TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 and the homotrimeric form of LYMPHOTOXIN-ALPHA. The receptor is abundantly expressed on T-LYMPHOCYTES and may play a role in regulating lymphocyte activation. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
| Descriptor ID |
D053240
|
| MeSH Number(s) |
D12.776.543.750.705.852.760.500 D12.776.543.750.830.850
|
| Concept/Terms |
Receptors, Tumor Necrosis Factor, Member 14- Receptors, Tumor Necrosis Factor, Member 14
- HveA Protein
- Tumor Necrosis Factor Receptor Superfamily, Member 14
- Tumor Necrosis Factor Receptor Subfamily, Member 14
- HVEM Protein
- Herpesvirus Entry Mediator
- Entry Mediator, Herpesvirus
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Tumor Necrosis Factor, Member 14".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Tumor Necrosis Factor [D12.776.543.750.705.852.760]
- Receptors, Tumor Necrosis Factor, Member 14 [D12.776.543.750.705.852.760.500]
- Receptors, Virus [D12.776.543.750.830]
- Receptors, Tumor Necrosis Factor, Member 14 [D12.776.543.750.830.850]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Tumor Necrosis Factor, Member 14".
This graph shows the total number of publications written about "Receptors, Tumor Necrosis Factor, Member 14" by people in this website by year, and whether "Receptors, Tumor Necrosis Factor, Member 14" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 2 | 0 | 2 |
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Below are the most recent publications written about "Receptors, Tumor Necrosis Factor, Member 14" by people in Profiles.
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Indolent In Situ B-Cell Neoplasms With MYC Rearrangements Show Somatic Mutations in MYC and TNFRSF14 by Next-generation Sequencing. Am J Surg Pathol. 2019 12; 43(12):1720-1725.
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High TNFRSF14 and low BTLA are associated with poor prognosis in Follicular Lymphoma and in Diffuse Large B-cell Lymphoma transformation. J Clin Exp Hematop. 2019; 59(1):1-16.
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HVEM and CD160: Regulators of Immunopathology During Malaria Blood-Stage. Front Immunol. 2018; 9:2611.
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Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT. J Mol Endocrinol. 2018 04; 60(3):171-183.
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Monoclonal Antibodies, Derived from Humans Vaccinated with the RV144 HIV Vaccine Containing the HVEM Binding Domain of Herpes Simplex Virus (HSV) Glycoprotein D, Neutralize HSV Infection, Mediate Antibody-Dependent Cellular Cytotoxicity, and Protect Mice from Ocular Challenge with HSV-1. J Virol. 2017 10 01; 91(19).
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Herpesvirus entry mediator (HVEM) attenuates signals mediated by the lymphotoxin ß receptor (LTßR) in human cells stimulated by the shared ligand LIGHT. Mol Immunol. 2014 Nov; 62(1):96-103.