"Loperamide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
| Descriptor ID |
D008139
|
| MeSH Number(s) |
D03.383.621.440
|
| Concept/Terms |
Loperamide Hydrochloride- Loperamide Hydrochloride
- Hydrochloride, Loperamide
- Loperamide Monohydrochloride
- Monohydrochloride, Loperamide
|
Below are MeSH descriptors whose meaning is more general than "Loperamide".
Below are MeSH descriptors whose meaning is more specific than "Loperamide".
This graph shows the total number of publications written about "Loperamide" by people in this website by year, and whether "Loperamide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
| 2017 | 2 | 1 | 3 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Loperamide" by people in Profiles.
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Loperamide associated torsades de pointes, in the setting of complete heart block at marginally supratherapeutic dosing (20mg/day). Clin Toxicol (Phila). 2019 11; 57(11):1123-1124.
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Travelers' Diarrhea and Other Gastrointestinal Symptoms Among Boston-Area International Travelers. Am J Trop Med Hyg. 2017 Jun; 96(6):1388-1393.
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Is it worth adding loperamide to antibiotic treatment of traveler?s diarrhea? Medwave. 2017 May 23; 17(Suppl 2):e6958.
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Bifidobacterium adolescentis Exerts Strain-Specific Effects on Constipation Induced by Loperamide in BALB/c Mice. Int J Mol Sci. 2017 Feb 20; 18(2).
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Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture. Antimicrob Agents Chemother. 2014 Aug; 58(8):4875-84.