Hemoglobinuria, Paroxysmal
"Hemoglobinuria, Paroxysmal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A condition characterized by the recurrence of HEMOGLOBINURIA caused by intravascular HEMOLYSIS. In cases occurring upon cold exposure (paroxysmal cold hemoglobinuria), usually after infections, there is a circulating antibody which is also a cold hemolysin. In cases occurring during or after sleep (paroxysmal nocturnal hemoglobinuria), the clonal hematopoietic stem cells exhibit a global deficiency of cell membrane proteins.
Descriptor ID |
D006457
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MeSH Number(s) |
C15.378.071.141.560 C15.378.190.625.460
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Concept/Terms |
Paroxysmal Cold Hemoglobinuria- Paroxysmal Cold Hemoglobinuria
- Hemoglobinuria, Paroxysmal Cold
- Paroxysmal Hemoglobinuria, Cold
- Cold Paroxysmal Hemoglobinuria
- Hemoglobinuria, Cold Paroxysmal
Paroxysmal Nocturnal Hemoglobinuria- Paroxysmal Nocturnal Hemoglobinuria
- Hemoglobinuria, Paroxysmal Nocturnal
- Marchiafava-Micheli Syndrome
- Marchiafava Micheli Syndrome
- Syndrome, Marchiafava-Micheli
- Paroxysmal Hemoglobinuria, Nocturnal
- Hemoglobinuria, Nocturnal Paroxysmal
- Nocturnal Paroxysmal Hemoglobinuria
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Below are MeSH descriptors whose meaning is more general than "Hemoglobinuria, Paroxysmal".
Below are MeSH descriptors whose meaning is more specific than "Hemoglobinuria, Paroxysmal".
This graph shows the total number of publications written about "Hemoglobinuria, Paroxysmal" by people in this website by year, and whether "Hemoglobinuria, Paroxysmal" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 1 | 0 | 1 |
2005 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
2013 | 1 | 0 | 1 |
2014 | 1 | 0 | 1 |
2016 | 1 | 1 | 2 |
2017 | 8 | 1 | 9 |
2018 | 7 | 0 | 7 |
2019 | 3 | 0 | 3 |
2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hemoglobinuria, Paroxysmal" by people in Profiles.
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COVID-19 vaccines induce severe hemolysis in paroxysmal nocturnal hemoglobinuria. Blood. 2021 07 01; 137(26):3670-3673.
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COVID-19 in patients with paroxysmal nocturnal haemoglobinuria: an Italian multicentre survey. Br J Haematol. 2021 09; 194(5):854-856.
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COVID19 infection in a patient with paroxysmal nocturnal hemoglobinuria: A case report. Medicine (Baltimore). 2021 May 21; 100(20):e25456.
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Internet-based patient survey on the consequences of COVID-19 lockdown on treatment and medical follow-up of patients with aplastic anemia or paroxysmal nocturnal hemoglobinuria in Germany. Eur J Haematol. 2021 May; 106(5):740-742.
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Severe COVID-19 infection in a patient with paroxysmal nocturnal hemoglobinuria on eculizumab therapy. Leuk Lymphoma. 2021 06; 62(6):1502-1505.
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Hemolytic crisis in a patient treated with eculizumab for paroxysmal nocturnal hemoglobinuria possibly triggered by SARS-CoV-2 (COVID-19): a case report. Ann Hematol. 2021 Mar; 100(3):841-842.
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Lip necrosis in a patient with paroxysmal nocturnal hemoglobinuria: Can it be triggered by COVID-19? J Cosmet Dermatol. 2020 Dec; 19(12):3168-3170.
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COVID-19 infection in patients on anti-complement therapy: The Leeds National Paroxysmal Nocturnal Haemoglobinuria service experience. Br J Haematol. 2020 10; 191(1):e1-e4.
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Mild Clinical Course of COVID-19 in 3 Patients Receiving Therapeutic Monoclonal Antibodies Targeting C5 Complement for Hematologic Disorders. Am J Case Rep. 2020 Sep 12; 21:e927418.
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COVID-19: A collision of complement, coagulation and inflammatory pathways. J Thromb Haemost. 2020 09; 18(9):2110-2117.