Topoisomerase I Inhibitors
"Topoisomerase I Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that inhibit the activity of DNA TOPOISOMERASE I.
| Descriptor ID |
D059004
|
| MeSH Number(s) |
D27.505.519.389.892.500 D27.505.954.248.794.500
|
| Concept/Terms |
Topoisomerase I Inhibitors- Topoisomerase I Inhibitors
- Inhibitors, Topoisomerase I
- Topoisomerase 1 Inhibitors
- Inhibitors, Topoisomerase 1
- DNA Topoisomerase I Inhibitors
- DNA Type 1 Topoisomerase Inhibitors
|
Below are MeSH descriptors whose meaning is more general than "Topoisomerase I Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Topoisomerase I Inhibitors".
This graph shows the total number of publications written about "Topoisomerase I Inhibitors" by people in this website by year, and whether "Topoisomerase I Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2017 | 3 | 0 | 3 |
| 2018 | 5 | 0 | 5 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Topoisomerase I Inhibitors" by people in Profiles.
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TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation. Cell. 2021 05 13; 184(10):2618-2632.e17.
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The AI-discovered aetiology of COVID-19 and rationale of the irinotecan+ etoposide combination therapy for critically ill COVID-19 patients. Med Hypotheses. 2020 Nov; 144:110180.
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Periocular topotecan for vitreous seeds in retinoblastoma. Indian J Ophthalmol. 2018 Dec; 66(12):1833-1838.
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Characterization of new, efficient Mycobacterium tuberculosis topoisomerase-I inhibitors and their interaction with human ABC multidrug transporters. PLoS One. 2018; 13(9):e0202749.
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Two novel camptothecin derivatives inhibit colorectal cancer proliferation via induction of cell cycle arrest and apoptosis in vitro and in vivo. Eur J Pharm Sci. 2018 Oct 15; 123:546-559.
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The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy. J Natl Cancer Inst. 2018 07 01; 110(7):777-786.
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Eye salvage in diffuse anterior retinoblastoma using systemic chemotherapy with periocular and intravitreal topotecan. J AAPOS. 2018 06; 22(3):235-237.e2.
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Intravitreal topotecan in the management of refractory and recurrent vitreous seeds in retinoblastoma. Br J Ophthalmol. 2018 04; 102(4):490-495.
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Synthesis and biological evaluation of a D-ring-contracted analogue of lamellarin D. Bioorg Med Chem. 2017 11 15; 25(22):6137-6148.
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Machine learning and docking models for Mycobacterium tuberculosis topoisomerase I. Tuberculosis (Edinb). 2017 03; 103:52-60.