"Occludin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A MARVEL domain protein that binds to and regulates PROTEIN PHOSPHATASE 1. Occludin plays an important role in the formation and regulation of the TIGHT JUNCTION paracellular permeability barrier.
| Descriptor ID |
D062793
|
| MeSH Number(s) |
D12.776.543.488.500 D12.776.543.940.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Occludin".
Below are MeSH descriptors whose meaning is more specific than "Occludin".
This graph shows the total number of publications written about "Occludin" by people in this website by year, and whether "Occludin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
| 2017 | 0 | 4 | 4 |
| 2018 | 1 | 3 | 4 |
| 2019 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Occludin" by people in Profiles.
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Exposure of human intestinal epithelial cells and primary human hepatocytes to trypsin-like serine protease inhibitors with potential antiviral effect. J Enzyme Inhib Med Chem. 2021 Dec; 36(1):659-668.
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COVID-19 disrupts the blood-testis barrier through the induction of inflammatory cytokines and disruption of junctional proteins. Inflamm Res. 2021 Dec; 70(10-12):1165-1175.
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Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure. Eur Respir J. 2021 03; 57(3).
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Human-rat chimeric anti-occludin monoclonal antibodies inhibit hepatitis C virus infection. Biochem Biophys Res Commun. 2019 06 30; 514(3):785-790.
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Increased jejunal permeability in human obesity is revealed by a lipid challenge and is linked to inflammation and type 2 diabetes. J Pathol. 2018 10; 246(2):217-230.
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H3N2 influenza virus infection enhances oncostatin M expression in human nasal epithelium. Exp Cell Res. 2018 10 15; 371(2):322-329.
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Monoclonal Antibodies against Occludin Completely Prevented Hepatitis C Virus Infection in a Mouse Model. J Virol. 2018 04 15; 92(8).
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Beneficial effects of Rifaximin in post-infectious irritable bowel syndrome mouse model beyond gut microbiota. J Gastroenterol Hepatol. 2018 Feb; 33(2):443-452.
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Role of matrix metalloproteinase-2/9 (MMP2/9) in lead-induced changes in an in vitro blood-brain barrier model. Int J Biol Sci. 2017; 13(11):1351-1360.
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Rhubarb Monomers Protect Intestinal Mucosal Barrier in Sepsis via Junction Proteins. Chin Med J (Engl). 2017 May 20; 130(10):1218-1225.