"Concanavalin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A MANNOSE/GLUCOSE binding lectin isolated from the jack bean (Canavalia ensiformis). It is a potent mitogen used to stimulate cell proliferation in lymphocytes, primarily T-lymphocyte, cultures.
| Descriptor ID |
D003208
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| MeSH Number(s) |
D12.776.503.499.500 D12.776.765.678.500
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Concanavalin A".
Below are MeSH descriptors whose meaning is more specific than "Concanavalin A".
This graph shows the total number of publications written about "Concanavalin A" by people in this website by year, and whether "Concanavalin A" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Concanavalin A" by people in Profiles.
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Concanavalin A targeting N-linked glycans in spike proteins influence viral interactions. Dalton Trans. 2020 Oct 12; 49(39):13538-13543.
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CD8+ T cell/IL-33/ILC2 axis exacerbates the liver injury in Con A-induced hepatitis in T cell-transferred Rag2-deficient mice. Inflamm Res. 2019 Jan; 68(1):75-91.
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Chlordecone potentiates auto-immune hepatitis and promotes brain entry of MHV3 during viral hepatitis in mouse models. Toxicol Lett. 2018 Dec 15; 299:129-136.
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Toll-like receptor 5 signaling restrains T-cell/natural killer T-cell activation and protects against concanavalin A-induced hepatic injury. Hepatology. 2017 06; 65(6):2059-2073.
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Exploiting pH-Regulated Dimer-Tetramer Transformation of Concanavalin A to Develop Colorimetric Biosensing of Bacteria. Sci Rep. 2017 05 03; 7(1):1452.
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High-mobility group box 1 exacerbates concanavalin A-induced hepatic injury in mice. J Mol Med (Berl). 2010 Dec; 88(12):1289-98.
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Differential virological and immunological outcome of severe acute respiratory syndrome coronavirus infection in susceptible and resistant transgenic mice expressing human angiotensin-converting enzyme 2. J Virol. 2009 Jun; 83(11):5451-65.
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Detection of infectious bronchitis virus and specific anti- viral antibodies using a Concanavalin A-Sandwich-ELISA. Viral Immunol. 2005; 18(3):569-78.
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CD7 and CD28 are required for murine CD4+CD25+ regulatory T cell homeostasis and prevention of thyroiditis. J Immunol. 2004 Jan 15; 172(2):787-94.
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Leptin receptor (Ob-R) expression is induced in peripheral blood mononuclear cells by in vitro activation and in vivo in HIV-infected patients. Clin Exp Immunol. 2002 Jul; 129(1):119-24.