"Dapsone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sulfone active against a wide range of bacteria but mainly employed for its actions against MYCOBACTERIUM LEPRAE. Its mechanism of action is probably similar to that of the SULFONAMIDES which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with PYRIMETHAMINE in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)
| Descriptor ID |
D003622
|
| MeSH Number(s) |
D02.886.590.263
|
| Concept/Terms |
Dapsone- Dapsone
- DADPS
- Sulfonyldianiline
- Diaminodiphenylsulfone
- Diaphenylsulfone
- 4,4'-Diaminophenyl Sulfone
- 4,4' Diaminophenyl Sulfone
- Sulfone, 4,4'-Diaminophenyl
|
Below are MeSH descriptors whose meaning is more general than "Dapsone".
Below are MeSH descriptors whose meaning is more specific than "Dapsone".
This graph shows the total number of publications written about "Dapsone" by people in this website by year, and whether "Dapsone" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2017 | 6 | 4 | 10 |
| 2018 | 2 | 0 | 2 |
| 2019 | 2 | 1 | 3 |
| 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Dapsone" by people in Profiles.
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The influence of leprosy-related clinical and epidemiological variables in the occurrence and severity of COVID-19: A prospective real-world cohort study. PLoS Negl Trop Dis. 2021 07; 15(7):e0009635.
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Dapsone-induced methaemoglobinaemia in leprosy: a close mimic of 'happy hypoxia' in the COVID-19 pandemic. J Eur Acad Dermatol Venereol. 2021 09; 35(9):e568-e571.
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Pemphigus and COVID-19: Critical overview of management with a focus on treatment choice. Dermatol Ther. 2020 11; 33(6):e14265.
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4,4'-Diaminodiphenyl Sulfone (DDS) as an Inflammasome Competitor. Int J Mol Sci. 2020 Aug 19; 21(17).
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Dapsone for Unresponsive Granulomatous Rosacea. Am J Ther. 2020 May/Jun; 27(3):e304-e306.
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Dapsone, colchicine and olanzapine as treatment adjuncts to prevent COVID-19 associated adult respiratory distress syndrome (ARDS). Med Hypotheses. 2020 08; 141:109774.
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Dapsone and doxycycline could be potential treatment modalities for COVID-19. Med Hypotheses. 2020 07; 140:109768.
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Dapsone in immunoglobulin A-associated vasculitis. Eur J Pediatr. 2019 12; 178(12):1913-1914.
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Dapsone reduced acetic acid-induced inflammatory response in rat colon tissue through inhibition of NF-kB signaling pathway. Immunopharmacol Immunotoxicol. 2019 Dec; 41(6):607-613.
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Metabolic, pharmacokinetic, and toxicological issues surrounding dapsone. Expert Opin Drug Metab Toxicol. 2019 May; 15(5):367-379.