Chloramphenicol O-Acetyltransferase
"Chloramphenicol O-Acetyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. Since chloramphenicol 3-acetate does not bind to bacterial ribosomes and is not an inhibitor of peptidyltransferase, the enzyme is responsible for the naturally occurring chloramphenicol resistance in bacteria. The enzyme, for which variants are known, is found in both gram-negative and gram-positive bacteria. EC 2.3.1.28.
| Descriptor ID |
D015500
|
| MeSH Number(s) |
D08.811.913.050.134.170
|
| Concept/Terms |
Chloramphenicol O-Acetyltransferase- Chloramphenicol O-Acetyltransferase
- Chloramphenicol O Acetyltransferase
- O-Acetyltransferase, Chloramphenicol
- Chloramphenicol Transacetylase
- Transacetylase, Chloramphenicol
- CAT Enzyme
- Enzyme, CAT
- Chloramphenicol Acetyltransferase
- Acetyltransferase, Chloramphenicol
|
Below are MeSH descriptors whose meaning is more general than "Chloramphenicol O-Acetyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Chloramphenicol O-Acetyltransferase".
This graph shows the total number of publications written about "Chloramphenicol O-Acetyltransferase" by people in this website by year, and whether "Chloramphenicol O-Acetyltransferase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Chloramphenicol O-Acetyltransferase" by people in Profiles.
-
Identification of a novel transcriptional repressor (HEPIS) that interacts with nsp-10 of SARS coronavirus. Viral Immunol. 2008 Jun; 21(2):153-62.
-
A trimerizing GxxxG motif is uniquely inserted in the severe acute respiratory syndrome (SARS) coronavirus spike protein transmembrane domain. Biochemistry. 2006 Sep 26; 45(38):11349-56.
-
Functional characterization of heptad repeat 1 and 2 mutants of the spike protein of severe acute respiratory syndrome coronavirus. J Virol. 2006 Apr; 80(7):3225-37.
-
The nucleocapsid protein of severe acute respiratory syndrome-coronavirus inhibits the activity of cyclin-cyclin-dependent kinase complex and blocks S phase progression in mammalian cells. J Biol Chem. 2006 Apr 21; 281(16):10669-81.
-
Presence of an encephalomyocarditis virus internal ribosome entry site sequence in avian infectious bronchitis virus defective RNAs abolishes rescue by helper virus. J Virol. 2004 Mar; 78(6):2711-21.
-
Enhancement of defective RNA expression vectors as potential vaccine delivery systems for avian infectious bronchitis virus. Adv Exp Med Biol. 2001; 494:407-9.
-
Use of an infectious bronchitis virus D-RNA as an RNA vector. Adv Exp Med Biol. 2001; 494:507-12.
-
Use of defective RNAs containing reporter genes to investigate targeted recombination for avian infectious bronchitis virus. Adv Exp Med Biol. 2001; 494:513-8.
-
Identification of a noncanonical transcription initiation site for transcription of a subgenomic mRNA of mouse hepatitis virus. Adv Exp Med Biol. 2001; 494:563-70.
-
The leader RNA of coronavirus mouse hepatitis virus contains an enhancer-like element for subgenomic mRNA transcription. J Virol. 2000 Nov; 74(22):10571-80.