"Kallikrein-Kinin System" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A system of metabolic interactions by products produced in the distal nephron of the KIDNEY. These products include KALLIKREIN; KININS; KININASE I; KININASE II; and ENKEPHALINASE. This system participates in the control of renal functions. It interacts with the RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM to regulate BLOOD PRESSURE, generation of PROSTAGLANDINS, release of VASOPRESSINS, and WATER-ELECTROLYTE BALANCE.
| Descriptor ID |
D016234
|
| MeSH Number(s) |
G02.111.635.500.500 G03.493.485 G03.615.500.500 G07.410.810.500.500 G09.330.380.690
|
| Concept/Terms |
Kallikrein-Kinin System- Kallikrein-Kinin System
- Kallikrein Kinin System
- Kallikrein-Kinin Systems
- Systems, Kallikrein-Kinin
|
Below are MeSH descriptors whose meaning is more general than "Kallikrein-Kinin System".
Below are MeSH descriptors whose meaning is more specific than "Kallikrein-Kinin System".
This graph shows the total number of publications written about "Kallikrein-Kinin System" by people in this website by year, and whether "Kallikrein-Kinin System" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 2 | 1 | 3 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Kallikrein-Kinin System" by people in Profiles.
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Role of the Renin-Angiotensin-Aldosterone and Kinin-Kallikrein Systems in the Cardiovascular Complications of COVID-19 and Long COVID. Int J Mol Sci. 2021 Jul 31; 22(15).
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Targeted LC-MS/MS platform for the comprehensive determination of peptides in the kallikrein-kinin system. Anal Bioanal Chem. 2021 May; 413(11):2971-2984.
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SARS-CoV-2 suppresses anticoagulant and fibrinolytic gene expression in the lung. Elife. 2021 03 08; 10.
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The Outcome of Critically Ill COVID-19 Patients Is Linked to Thromboinflammation Dominated by the Kallikrein/Kinin System. Front Immunol. 2021; 12:627579.
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Safety and Outcomes Associated with the Pharmacological Inhibition of the Kinin-Kallikrein System in Severe COVID-19. Viruses. 2021 02 16; 13(2).
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Sensitive mass spectrometric determination of kinin-kallikrein system peptides in light of COVID-19. Sci Rep. 2021 02 04; 11(1):3061.
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Obesity and COVID-19: the ominous duet affecting the renin-angiotensin system. Minerva Endocrinol (Torino). 2021 06; 46(2):193-201.
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SARS-CoV-2 receptor is co-expressed with elements of the kinin-kallikrein, renin-angiotensin and coagulation systems in alveolar cells. Sci Rep. 2020 11 11; 10(1):19522.
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Emerging Mechanisms of Pulmonary Vasoconstriction in SARS-CoV-2-Induced Acute Respiratory Distress Syndrome (ARDS) and Potential Therapeutic Targets. Int J Mol Sci. 2020 Oct 29; 21(21).
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Angiotensin-converting enzyme 2, the complement system, the kallikrein-kinin system, type-2 diabetes, interleukin-6, and their interactions regarding the complex COVID-19 pathophysiological crossroads. J Renin Angiotensin Aldosterone Syst. 2020 Oct-Dec; 21(4):1470320320979097.