"Apolipoprotein A-I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. This protein serves as an acceptor for CHOLESTEROL released from cells thus promoting efflux of cholesterol to HDL then to the LIVER for excretion from the body (reverse cholesterol transport). It also acts as a cofactor for LECITHIN CHOLESTEROL ACYLTRANSFERASE that forms CHOLESTEROL ESTERS on the HDL particles. Mutations of this gene APOA1 cause HDL deficiency, such as in FAMILIAL ALPHA LIPOPROTEIN DEFICIENCY DISEASE and in some patients with TANGIER DISEASE.
Descriptor ID |
D016632
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MeSH Number(s) |
D10.532.091.200.100 D12.776.070.400.200.100 D12.776.521.120.200.100
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Concept/Terms |
Apolipoprotein A-I- Apolipoprotein A-I
- Apolipoprotein A I
- Apo A-I
- Apo A1
- Apolipoprotein AI
- ApoA-1
- ApoA-I
- Apolipoprotein A-1
- Apolipoprotein A 1
- Apolipoprotein A1
- Apo A-1
- Apo AI
Pro-Apolipoprotein A-I- Pro-Apolipoprotein A-I
- Pro Apolipoprotein A I
- Pro-Apo A-I
- Pro Apo A I
- Proapolipoprotein AI
- Apolipoprotein AI Propeptide
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Below are MeSH descriptors whose meaning is more general than "Apolipoprotein A-I".
Below are MeSH descriptors whose meaning is more specific than "Apolipoprotein A-I".
This graph shows the total number of publications written about "Apolipoprotein A-I" by people in this website by year, and whether "Apolipoprotein A-I" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 2 | 2 |
2003 | 1 | 0 | 1 |
2004 | 1 | 0 | 1 |
2010 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2017 | 5 | 4 | 9 |
2018 | 9 | 4 | 13 |
2019 | 3 | 1 | 4 |
2020 | 1 | 0 | 1 |
2021 | 1 | 2 | 3 |
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Below are the most recent publications written about "Apolipoprotein A-I" by people in Profiles.
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SARS-CoV-2 infection as a trigger of humoral response against apolipoprotein A-1. Eur J Clin Invest. 2021 Nov; 51(11):e13661.
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Low serum level of apolipoprotein A1 may predict the severity of COVID-19: A retrospective study. J Clin Lab Anal. 2021 Aug; 35(8):e23911.
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Baseline cardiometabolic profiles and SARS-CoV-2 infection in the UK Biobank. PLoS One. 2021; 16(4):e0248602.
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Association of serum HDL-cholesterol and apolipoprotein A1 levels with risk of severe SARS-CoV-2 infection. J Lipid Res. 2021; 62:100061.
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Lipid metabolism changes in patients with severe COVID-19. Clin Chim Acta. 2021 Jun; 517:66-73.
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Altered high-density lipoprotein composition and functions during severe COVID-19. Sci Rep. 2021 01 27; 11(1):2291.
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Performance of serum apolipoprotein-A1 as a sentinel of Covid-19. PLoS One. 2020; 15(11):e0242306.
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COVID-19-Associated dyslipidemia: Implications for mechanism of impaired resolution and novel therapeutic approaches. FASEB J. 2020 08; 34(8):9843-9853.
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Identification, expression analysis, and antibacterial activity of Apolipoprotein A-I from amphioxus (Branchiostoma belcheri). Comp Biochem Physiol B Biochem Mol Biol. 2019 Dec; 238:110329.
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ELISA methods comparison for the detection of auto-antibodies against apolipoprotein A1. J Immunol Methods. 2019 06; 469:33-41.