"Genes, erbB-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The proto-oncogene c-erbB-1 codes for the epidermal growth factor receptor. Its name originates from the viral homolog v-erbB which was isolated from an avian erythroblastosis virus (AEV) where it was contained as a fragment of the chicken c-ErbB-1 gene lacking the amino-terminal ligand-binding domain. Overexpression of erbB-1 genes occurs in a wide range of tumors, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c-erbB-1 gene is located in the chromosomal region 7p14 and 7p12.
| Descriptor ID |
D018773
|
| MeSH Number(s) |
G05.360.340.024.340.375.500.791.295.300
|
| Concept/Terms |
Genes, erbB-1- Genes, erbB-1
- Genes, erbB1
- Gene, erbB1
- erbB1 Gene
- erbB1 Genes
- erbB-1 Genes
- erbB 1 Genes
- erbB-1 Gene
v-erbB Genes- v-erbB Genes
- v erbB Genes
- v-erbB Gene
- v-erbB Oncogenes
- v erbB Oncogenes
- v-erbB Oncogene
c-erbB-1 Genes- c-erbB-1 Genes
- c erbB 1 Genes
- c-erbB-1 Gene
- EGFR Genes
- Epidermal Growth Factor Receptor Genes
- c-erbB-1 Proto-Oncogenes
- c erbB 1 Proto Oncogenes
- c-erbB-1 Proto-Oncogene
- Genes, EGFR
- EGFR Gene
|
Below are MeSH descriptors whose meaning is more general than "Genes, erbB-1".
Below are MeSH descriptors whose meaning is more specific than "Genes, erbB-1".
This graph shows the total number of publications written about "Genes, erbB-1" by people in this website by year, and whether "Genes, erbB-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 1 | 2 |
| 2017 | 1 | 1 | 2 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genes, erbB-1" by people in Profiles.
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Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC. N Engl J Med. 2018 Jun 14; 378(24):2288-2301.
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Comparative efficacy and safety of second-line treatments for advanced non-small cell lung cancer with wild-type or unknown status for epidermal growth factor receptor: a systematic review and network meta-analysis. BMC Med. 2017 10 30; 15(1):193.
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MicroRNA pharmacogenomics based integrated model of miR-17-92 cluster in sorafenib resistant HCC cells reveals a strategy to forestall drug resistance. Sci Rep. 2017 09 13; 7(1):11448.
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Epidermal growth factor receptor (EGFR) mutations and expression in squamous cell carcinoma of the esophagus in central Asia. BMC Cancer. 2012 Dec 17; 12:602.
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Prognostic value of TP53, KRAS and EGFR mutations in nonsmall cell lung cancer: the EUELC cohort. Eur Respir J. 2012 Jul; 40(1):177-84.