Long Interspersed Nucleotide Elements
"Long Interspersed Nucleotide Elements" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly repeated sequences, 6K-8K base pairs in length, which contain RNA polymerase II promoters. They also have an open reading frame that is related to the reverse transcriptase of retroviruses but they do not contain LTRs (long terminal repeats). Copies of the LINE 1 (L1) family form about 15% of the human genome. The jockey elements of Drosophila are LINEs.
Descriptor ID |
D020084
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MeSH Number(s) |
G02.111.570.080.708.330.800.400 G05.360.080.708.330.800.400 G05.360.340.024.425.800.400
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Concept/Terms |
Long Interspersed Nucleotide Elements- Long Interspersed Nucleotide Elements
- LINE Repeat Sequences
- LINE Repeat Sequence
- Repeat Sequence, LINE
- Repeat Sequences, LINE
- Sequence, LINE Repeat
- Sequences, LINE Repeat
- Long Interspersed DNA Sequence Elements
LINE-1 Elements- LINE-1 Elements
- Element, LINE-1
- Elements, LINE-1
- LINE 1 Elements
- LINE-1 Element
- L1 Elements
- Element, L1
- Elements, L1
- L1 Element
Jockey Elements- Jockey Elements
- Element, Jockey
- Elements, Jockey
- Jockey Element
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Below are MeSH descriptors whose meaning is more general than "Long Interspersed Nucleotide Elements".
Below are MeSH descriptors whose meaning is more specific than "Long Interspersed Nucleotide Elements".
This graph shows the total number of publications written about "Long Interspersed Nucleotide Elements" by people in this website by year, and whether "Long Interspersed Nucleotide Elements" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 0 | 1 | 1 |
2017 | 3 | 2 | 5 |
2018 | 3 | 0 | 3 |
2019 | 1 | 0 | 1 |
2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Long Interspersed Nucleotide Elements" by people in Profiles.
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No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing. Cell Rep. 2021 08 17; 36(7):109530.
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Do coronavirus genes slip into human chromosomes? Science. 2021 05 14; 372(6543):674-675.
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Noncoding RNAs: modulators and modulatable players during infection-induced stress response. Brief Funct Genomics. 2021 03 02; 20(1):28-41.
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LINE-1-Mediated AluYa5 Insertion Underlying Complete Autosomal Recessive IFN-?R1 Deficiency. J Clin Immunol. 2019 10; 39(7):739-742.
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Comprehensive analysis of HPV infection, EGFR exon 20 mutations and LINE1 hypomethylation as risk factors for malignant transformation of sinonasal-inverted papilloma to squamous cell carcinoma. Int J Cancer. 2019 03 15; 144(6):1313-1320.
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Resveratrol Modulates SIRT1 and DNMT Functions and Restores LINE-1 Methylation Levels in ARPE-19 Cells under Oxidative Stress and Inflammation. Int J Mol Sci. 2018 Jul 20; 19(7).
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Prenatal phthalate exposure, birth outcomes and DNA methylation of Alu and LINE-1 repetitive elements: A pilot study in China. Chemosphere. 2018 Sep; 206:759-765.
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Aberrant promoter methylation of multiple genes in VSMC proliferation induced by Hcy. Mol Med Rep. 2017 Nov; 16(5):7775-7783.
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Methylation status of IGF2 DMR and LINE1 in leukocyte DNA provides distinct clinicopathological features of gastric cancer patients. Clin Exp Med. 2018 May; 18(2):215-220.
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Evaluation of DNA methylation of inflammatory genes following treatment of chronic periodontitis: A pilot case-control study. J Clin Periodontol. 2017 Sep; 44(9):905-914.