CD4-Positive T-Lymphocytes
"CD4-Positive T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.
| Descriptor ID |
D015496
|
| MeSH Number(s) |
A11.118.637.555.567.569.200 A15.145.229.637.555.567.569.200 A15.382.490.555.567.569.200
|
| Concept/Terms |
CD4-Positive T-Lymphocytes- CD4-Positive T-Lymphocytes
- CD4 Positive T Lymphocytes
- CD4-Positive T-Lymphocyte
- T-Lymphocyte, CD4-Positive
- T-Lymphocytes, CD4-Positive
- CD4-Positive Lymphocytes
- CD4-Positive Lymphocyte
- Lymphocyte, CD4-Positive
- Lymphocytes, CD4-Positive
- T4 Cells
- T4 Cell
- T4 Lymphocytes
- T4 Lymphocyte
|
Below are MeSH descriptors whose meaning is more general than "CD4-Positive T-Lymphocytes".
Below are MeSH descriptors whose meaning is more specific than "CD4-Positive T-Lymphocytes".
This graph shows the total number of publications written about "CD4-Positive T-Lymphocytes" by people in this website by year, and whether "CD4-Positive T-Lymphocytes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1997 | 3 | 0 | 3 |
| 2000 | 2 | 1 | 3 |
| 2001 | 2 | 2 | 4 |
| 2002 | 1 | 2 | 3 |
| 2003 | 2 | 3 | 5 |
| 2004 | 4 | 3 | 7 |
| 2005 | 1 | 1 | 2 |
| 2006 | 3 | 2 | 5 |
| 2007 | 3 | 3 | 6 |
| 2008 | 4 | 3 | 7 |
| 2009 | 10 | 3 | 13 |
| 2010 | 4 | 5 | 9 |
| 2011 | 5 | 5 | 10 |
| 2012 | 4 | 4 | 8 |
| 2013 | 5 | 4 | 9 |
| 2014 | 8 | 5 | 13 |
| 2015 | 2 | 4 | 6 |
| 2016 | 4 | 6 | 10 |
| 2017 | 112 | 104 | 216 |
| 2018 | 85 | 73 | 158 |
| 2019 | 32 | 43 | 75 |
| 2020 | 29 | 39 | 68 |
| 2021 | 30 | 39 | 69 |
To return to the timeline, click here.
Below are the most recent publications written about "CD4-Positive T-Lymphocytes" by people in Profiles.
-
Are the Healthy Vulnerable? Cytomegalovirus Seropositivity in Healthy Adults Is Associated With Accelerated Epigenetic Age and Immune Dysregulation. J Infect Dis. 2022 02 01; 225(3):443-452.
-
Defining Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Placentitis. Arch Pathol Lab Med. 2021 11 01; 145(11):1341-1349.
-
Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination. Science. 2021 10 08; 374(6564):eabh1823.
-
CD8+PD-L1+CXCR3+ polyfunctional T cell abundances are associated with survival in critical SARS-CoV-2-infected patients. JCI Insight. 2021 09 22; 6(18).
-
Large-Scale Identification of T-Cell Epitopes Derived From Severe Acute Respiratory Syndrome Coronavirus 2 for the Development of Peptide Vaccines Against Coronavirus Disease 2019. J Infect Dis. 2021 09 17; 224(6):956-966.
-
Profound Treg perturbations correlate with COVID-19 severity. Proc Natl Acad Sci U S A. 2021 09 14; 118(37).
-
Hemophagocytic lymphohistiocytosis following ChAdOx1 nCov-19 vaccination. J Med Virol. 2022 01; 94(1):14-16.
-
The cytokines HGF and CXCL13 predict the severity and the mortality in COVID-19 patients. Nat Commun. 2021 08 09; 12(1):4888.
-
Reduction and exhausted features of T lymphocytes under serological changes, and prognostic factors in COVID-19 progression. Mol Immunol. 2021 10; 138:121-127.
-
Unsupervised machine learning reveals key immune cell subsets in COVID-19, rhinovirus infection, and cancer therapy. Elife. 2021 08 05; 10.