Pyrroline Carboxylate Reductases
"Pyrroline Carboxylate Reductases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of enzymes that catalyze the reduction of 1-pyrroline carboxylate to proline in the presence of NAD(P)H. Includes both the 2-oxidoreductase (EC 1.5.1.1) and the 5-oxidoreductase (EC 1.5.1.2). The former also reduces 1-piperidine-2-carboxylate to pipecolate and the latter also reduces 1-pyrroline-3-hydroxy-5-carboxylate to hydroxyproline.
| Descriptor ID |
D011762
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| MeSH Number(s) |
D08.811.682.662.695
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pyrroline Carboxylate Reductases".
Below are MeSH descriptors whose meaning is more specific than "Pyrroline Carboxylate Reductases".
This graph shows the total number of publications written about "Pyrroline Carboxylate Reductases" by people in this website by year, and whether "Pyrroline Carboxylate Reductases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pyrroline Carboxylate Reductases" by people in Profiles.
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De Barsy Syndrome: a genetically heterogeneous autosomal recessive cutis laxa syndrome related to P5CS and PYCR1 dysfunction. Am J Med Genet A. 2012 Apr; 158A(4):927-31.
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Purification, characterization, and crystallization of human pyrroline-5-carboxylate reductase. Protein Expr Purif. 2006 Sep; 49(1):83-7.