"Silymarin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mixture of flavonoids extracted from seeds of the MILK THISTLE, Silybum marianum. It consists primarily of silybin and its isomers, silicristin and silidianin. Silymarin displays antioxidant and membrane stabilizing activity. It protects various tissues and organs against chemical injury, and shows potential as an antihepatoxic agent.
| Descriptor ID |
D012838
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| MeSH Number(s) |
D03.383.663.283.266.450.268.777 D03.633.100.150.266.450.268.777
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Silymarin".
Below are MeSH descriptors whose meaning is more specific than "Silymarin".
This graph shows the total number of publications written about "Silymarin" by people in this website by year, and whether "Silymarin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 2 | 0 | 2 |
| 2017 | 4 | 2 | 6 |
| 2018 | 0 | 2 | 2 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Silymarin" by people in Profiles.
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Phyto-pharmacological perspective of Silymarin: A potential prophylactic or therapeutic agent for COVID-19, based on its promising immunomodulatory, anti-coagulant and anti-viral property. Phytother Res. 2021 Aug; 35(8):4246-4257.
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SARS-CoV-2 Main Protease Active Site Ligands in the Human Metabolome. Molecules. 2021 Mar 05; 26(5).
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Metabolic effect of berberine-silymarin association: A meta-analysis of randomized, double-blind, placebo-controlled clinical trials. Phytother Res. 2019 Apr; 33(4):862-870.
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Heat shock protein 47 as indispensible participant in liver fibrosis: Possible protective effect of lactoferrin. IUBMB Life. 2018 08; 70(8):795-805.
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Milk thistle (Silybum marianum): A concise overview on its chemistry, pharmacological, and nutraceutical uses in liver diseases. Phytother Res. 2018 Nov; 32(11):2202-2213.
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Silymarin: An option to treat non-alcoholic fatty liver disease. World J Gastroenterol. 2017 Dec 21; 23(47):8437-8438.
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Addition of silymarin to renin-angiotensin system blockers in normotensive patients with type 2 diabetes mellitus and proteinuria: a prospective randomized trial. Int Urol Nephrol. 2017 Dec; 49(12):2195-2204.
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Hepatoprotective naphthalene diglucoside from Neanotis wightiana aerial parts. Phytomedicine. 2017 Sep 15; 33:14-20.
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NAFLD and Atherosclerosis Are Prevented by a Natural Dietary Supplement Containing Curcumin, Silymarin, Guggul, Chlorogenic Acid and Inulin in Mice Fed a High-Fat Diet. Nutrients. 2017 May 13; 9(5).
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Therapeutic effects of silibinin on LPS-induced acute lung injury by inhibiting NLRP3 and NF-?B signaling pathways. Microb Pathog. 2017 Jul; 108:104-108.