"Dopamine Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME.
| Descriptor ID |
D018492
|
| MeSH Number(s) |
D27.505.519.625.150.175 D27.505.696.577.150.175
|
| Concept/Terms |
Dopamine Antagonists- Dopamine Antagonists
- Dopaminergic Antagonists
- Dopamine Blockers
- Blockers, Dopamine
- Antagonists, Dopamine Receptor
- Receptor Antagonists, Dopamine
- Antagonists, Dopaminergic
- Dopamine Receptor Antagonists
- Antagonists, Dopamine
|
Below are MeSH descriptors whose meaning is more general than "Dopamine Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Dopamine Antagonists".
This graph shows the total number of publications written about "Dopamine Antagonists" by people in this website by year, and whether "Dopamine Antagonists" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 4 | 6 |
| 2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Dopamine Antagonists" by people in Profiles.
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Enrichment-induced differences in methamphetamine drug discrimination in male rats. Pharmacol Biochem Behav. 2019 04; 179:80-88.
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Amisulpride for the Rescue Treatment of Postoperative Nausea or Vomiting in Patients Failing Prophylaxis: A Randomized, Placebo-controlled Phase III Trial. Anesthesiology. 2019 02; 130(2):203-212.
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Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness. N Engl J Med. 2018 12 27; 379(26):2506-2516.
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Multiple perianal ulcers due to suppositories. Australas J Dermatol. 2019 Feb; 60(1):50-52.
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Searching for Replicable Dopamine-Related Findings in Gambling Disorder. Biol Psychiatry. 2018 06 15; 83(12):984-986.
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Amisulpride Prevents Postoperative Nausea and Vomiting in Patients at High Risk: A Randomized, Double-blind, Placebo-controlled Trial. Anesthesiology. 2018 06; 128(6):1099-1106.
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Clinical risk factors for the development of tardive dyskinesia. J Neurol Sci. 2018 06 15; 389:21-27.
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Motor learning and metaplasticity in striatal neurons: relevance for Parkinson's disease. Brain. 2018 02 01; 141(2):505-520.
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Multiple organic cation transporters contribute to the renal transport of sulpiride. Biopharm Drug Dispos. 2017 Dec; 38(9):526-534.
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Threshold of Dopamine D2/3 Receptor Occupancy for Hyperprolactinemia in Older Patients With Schizophrenia. J Clin Psychiatry. 2016 Dec; 77(12):e1557-e1563.