"Glucosylceramidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycosidase that hydrolyzes a glucosylceramide to yield free ceramide plus glucose. Deficiency of this enzyme leads to abnormally high concentrations of glucosylceramide in the brain in GAUCHER DISEASE. EC 3.2.1.45.
| Descriptor ID |
D005962
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| MeSH Number(s) |
D08.811.277.450.420.412
|
| Concept/Terms |
Glucosylceramidase- Glucosylceramidase
- beta-Glucocerebrosidase
- beta Glucocerebrosidase
- Acid beta-Glucosidase
- Acid beta Glucosidase
- beta-Glucosidase, Acid
- Glucocerebroside beta-Glucosidase
- Glucocerebroside beta Glucosidase
- beta-Glucosidase, Glucocerebroside
- Glucosylceramide beta-Glucosidase
- Glucosylceramide beta Glucosidase
- beta-Glucosidase, Glucosylceramide
- Glucosylsphingosine Glucosyl Hydrolase
- Glucosyl Hydrolase, Glucosylsphingosine
- Hydrolase, Glucosylsphingosine Glucosyl
- Glucosyl Ceramidase
- Ceramidase, Glucosyl
- Glucocerebrosidase
|
Below are MeSH descriptors whose meaning is more general than "Glucosylceramidase".
Below are MeSH descriptors whose meaning is more specific than "Glucosylceramidase".
This graph shows the total number of publications written about "Glucosylceramidase" by people in this website by year, and whether "Glucosylceramidase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 2 | 1 | 3 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glucosylceramidase" by people in Profiles.
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Direct and indirect effects of the SARS-CoV-2 pandemic on Gaucher Disease patients in Spain: Time to reconsider home-based therapies? Blood Cells Mol Dis. 2020 11; 85:102478.
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Prodromal substantia nigra sonography undermines suggested association between substrate accumulation and the risk for GBA-related Parkinson's disease. Eur J Neurol. 2019 07; 26(7):1013-1018.
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Evidence for the Involvement of Lipid Rafts and Plasma Membrane Sphingolipid Hydrolases in Pseudomonas aeruginosa Infection of Cystic Fibrosis Bronchial Epithelial Cells. Mediators Inflamm. 2017; 2017:1730245.
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Cognitive impairment in Glucocerebrosidase (GBA)-associated PD: Not primarily associated with cerebrospinal fluid Abeta and Tau profiles. Mov Disord. 2017 Dec; 32(12):1780-1783.
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Cerebrospinal fluid ß-glucocerebrosidase activity is reduced in parkinson's disease patients. Mov Disord. 2017 Oct; 32(10):1423-1431.
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GBA-associated parkinsonism and dementia: beyond a-synucleinopathies? Eur J Neurol. 2016 Mar; 23(3):520-6.
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Evaluation of micro-parallel liquid chromatography as a method for HTS-coupled actives verification. Assay Drug Dev Technol. 2007 Dec; 5(6):815-24.