"Receptor, TIE-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TIE receptor tyrosine kinase that is found almost exclusively on ENDOTHELIAL CELLS. It is required for both normal embryonic vascular development (NEOVASCULARIZATION, PHYSIOLOGIC) and tumor angiogenesis (NEOVASCULARIZATION, PATHOLOGIC).
| Descriptor ID |
D042787
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| MeSH Number(s) |
D08.811.913.696.620.682.725.400.925.500 D12.776.543.750.630.687.500
|
| Concept/Terms |
Receptor, TIE-2- Receptor, TIE-2
- Receptor, TIE 2
- TIE-2 Receptor
- TIE2 Tyrosine Kinase
- Tyrosine Kinase, TIE2
- TIE-2 Receptor Tyrosine Kinase
- TIE 2 Receptor Tyrosine Kinase
- Tek Receptor
- Receptor, Tek
- Tie2 Receptor
- Receptor, Tie2
- TIE-2-RTK
- Angiopoietin Receptor Tie-2
- Angiopoietin Receptor Tie 2
- Receptor Tie-2, Angiopoietin
- Tie-2, Angiopoietin Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptor, TIE-2".
Below are MeSH descriptors whose meaning is more specific than "Receptor, TIE-2".
This graph shows the total number of publications written about "Receptor, TIE-2" by people in this website by year, and whether "Receptor, TIE-2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2017 | 4 | 0 | 4 |
| 2018 | 3 | 1 | 4 |
| 2019 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptor, TIE-2" by people in Profiles.
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Designed proteins assemble antibodies into modular nanocages. Science. 2021 04 02; 372(6537).
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PDE5 Inhibition Stimulates Tie2-Expressing Monocytes and Angiopoietin-1 Restoring Angiogenic Homeostasis in Diabetes. J Clin Endocrinol Metab. 2019 07 01; 104(7):2623-2636.
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Dysregulation of circulating sTie2 and sHER2 in HIV-infected women with preeclampsia. Hypertens Pregnancy. 2019 May; 38(2):89-95.
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Discovery of novel anti-angiogenesis agents. Part 10: Multi-target inhibitors of VEGFR-2, Tie-2 and EphB4 incorporated with 1,2,3-triazol. Eur J Med Chem. 2019 Feb 01; 163:1-9.
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Molecular Regulation of Acute Tie2 Suppression in Sepsis. Crit Care Med. 2018 09; 46(9):e928-e936.
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Delineating Pro-Angiogenic Myeloid Cells in Cancer Therapy. Int J Mol Sci. 2018 Aug 29; 19(9).
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Tie2 protects the vasculature against thrombus formation in systemic inflammation. J Clin Invest. 2018 04 02; 128(4):1471-1484.
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Discovery of novel anti-angiogenesis agents. Part 7: Multitarget inhibitors of VEGFR-2, TIE-2 and EphB4. Eur J Med Chem. 2017 Dec 01; 141:506-518.
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Angiopoietin receptor TEK interacts with CYP1B1 in primary congenital glaucoma. Hum Genet. 2017 08; 136(8):941-949.
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Angiopoietin-2 acts as a survival factor for chronic lymphocytic leukemia B cells throughout Tie-2 receptor engagement. Hematol Oncol. 2018 Feb; 36(1):372-375.