Jumonji Domain-Containing Histone Demethylases
"Jumonji Domain-Containing Histone Demethylases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of histone demethylases that share a conserved Jumonji C domain. The enzymes function via an iron-dependent dioxygenase mechanism that couples the conversion of 2-oxoglutarate to succinate to the hydroxylation of N-methyl groups.
Descriptor ID |
D056484
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MeSH Number(s) |
D08.811.682.662.582.475.500 D08.811.682.690.416.388
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Jumonji Domain-Containing Histone Demethylases".
Below are MeSH descriptors whose meaning is more specific than "Jumonji Domain-Containing Histone Demethylases".
This graph shows the total number of publications written about "Jumonji Domain-Containing Histone Demethylases" by people in this website by year, and whether "Jumonji Domain-Containing Histone Demethylases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2017 | 6 | 0 | 6 |
2018 | 6 | 0 | 6 |
2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Jumonji Domain-Containing Histone Demethylases" by people in Profiles.
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Integrative analysis of miRNA and mRNA sequencing data reveals potential regulatory mechanisms of ACE2 and TMPRSS2. PLoS One. 2020; 15(7):e0235987.
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Irisin modulates genes associated with severe coronavirus disease (COVID-19) outcome in human subcutaneous adipocytes cell culture. Mol Cell Endocrinol. 2020 09 15; 515:110917.
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The modification of mitochondrial energy metabolism and histone of goat somatic cells under small molecules compounds induction. Reprod Domest Anim. 2019 Feb; 54(2):138-149.
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Interplay among H3K9-editing enzymes SUV39H1, JMJD2C and SRC-1 drives p66Shc transcription and vascular oxidative stress in obesity. Eur Heart J. 2019 01 21; 40(4):383-391.
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Little imaginal discs, a Trithorax group member, is a constituent of nuclear matrix of Drosophila melanogaster embryos. J Biosci. 2018 Sep; 43(4):621-633.
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KDM5 histone demethylases repress immune response via suppression of STING. PLoS Biol. 2018 08; 16(8):e2006134.
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Notch-effector CSL promotes squamous cell carcinoma by repressing histone demethylase KDM6B. J Clin Invest. 2018 06 01; 128(6):2581-2599.
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JMJD3 is involved in neutrophil membrane proteinase 3 overexpression during the hyperinflammatory response in early sepsis. Int Immunopharmacol. 2018 Jun; 59:40-46.
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FBXL10 contributes to the development of diffuse large B-cell lymphoma by epigenetically enhancing ERK1/2 signaling pathway. Cell Death Dis. 2018 01 19; 9(2):46.
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HPV16 E6 and E7 upregulate the histone lysine demethylase KDM2B through the c-MYC/miR-146a-5p axys. Oncogene. 2018 03; 37(12):1654-1668.