ATP Binding Cassette Transporter 1
"ATP Binding Cassette Transporter 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A superfamily of large integral ATP-binding cassette membrane proteins whose expression pattern is consistent with a role in lipid (cholesterol) efflux. It is implicated in TANGIER DISEASE characterized by accumulation of cholesteryl ester in various tissues.
Descriptor ID |
D064286
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MeSH Number(s) |
D12.776.157.530.100.190.500 D12.776.395.550.020.381.500 D12.776.543.550.192.381.500 D12.776.543.585.100.190.500
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Concept/Terms |
ATP Binding Cassette Transporter 1- ATP Binding Cassette Transporter 1
- ATP-Binding Cassette Sub-Family A Member 1
- ATP Binding Cassette Sub Family A Member 1
- CERP Protein
- Protein, CERP
- ABCA1 Protein
- Protein, ABCA1
- Cholesterol-Efflux Regulatory Protein
- Cholesterol Efflux Regulatory Protein
- Protein, Cholesterol-Efflux Regulatory
- Regulatory Protein, Cholesterol-Efflux
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Below are MeSH descriptors whose meaning is more general than "ATP Binding Cassette Transporter 1".
Below are MeSH descriptors whose meaning is more specific than "ATP Binding Cassette Transporter 1".
This graph shows the total number of publications written about "ATP Binding Cassette Transporter 1" by people in this website by year, and whether "ATP Binding Cassette Transporter 1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2009 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2017 | 2 | 0 | 2 |
2018 | 3 | 5 | 8 |
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Below are the most recent publications written about "ATP Binding Cassette Transporter 1" by people in Profiles.
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USF1 deficiency alleviates inflammation, enhances cholesterol efflux and prevents cholesterol accumulation in macrophages. Lipids Health Dis. 2018 Dec 13; 17(1):285.
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High-Density Lipoprotein Components and Functionality in Cancer: State-of-the-Art. Trends Endocrinol Metab. 2019 01; 30(1):12-24.
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Reply to "Osteopontin inhibits macrophage cholesterol efflux via NF-?B/ABCA1 pathway". Int J Cardiol. 2018 09 15; 267:195.
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Hypoalphalipoproteinemia and BRAFV600E Mutation Are Major Predictors of Aortic Infiltration in the Erdheim-Chester Disease. Arterioscler Thromb Vasc Biol. 2018 08; 38(8):1913-1925.
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Chlamydia pneumoniae Hijacks a Host Autoregulatory IL-1ß Loop to Drive Foam Cell Formation and Accelerate Atherosclerosis. Cell Metab. 2018 09 04; 28(3):432-448.e4.
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Mindin deficiency in macrophages protects against foam cell formation and atherosclerosis by targeting LXR-ß. Clin Sci (Lond). 2018 06 15; 132(11):1199-1213.
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Interleukin-32 upregulates the expression of ABCA1 and ABCG1 resulting in reduced intracellular lipid concentrations in primary human hepatocytes. Atherosclerosis. 2018 04; 271:193-202.
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A novel index including SNPs for the screening of nonalcoholic fatty liver disease among elder Chinese: A population-based study. Medicine (Baltimore). 2018 Mar; 97(13):e0272.
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Reduced platelet count, but no major platelet function abnormalities, are associated with loss-of-function ATP-binding cassette-1 gene mutations. Clin Sci (Lond). 2017 Aug 15; 131(16):2095-2107.
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Exposure to High Glucose Concentration Decreases Cell Surface ABCA1 and HDL Biogenesis in Hepatocytes. J Atheroscler Thromb. 2017 Nov 01; 24(11):1132-1149.