"HIV Fusion Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Inhibitors of the fusion of HIV to host cells, preventing viral entry. This includes compounds that block attachment of HIV ENVELOPE PROTEIN GP120 to CD4 RECEPTORS.
| Descriptor ID |
D023581
|
| MeSH Number(s) |
D27.505.519.957.500 D27.505.954.122.388.077.088.209 D27.505.954.122.388.538.500
|
| Concept/Terms |
HIV Fusion Inhibitors- HIV Fusion Inhibitors
- HIV Cell Fusion Inhibitors
- HIV Fusion Protein Inhibitors
- Fusion Inhibitors, HIV
|
Below are MeSH descriptors whose meaning is more general than "HIV Fusion Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "HIV Fusion Inhibitors".
This graph shows the total number of publications written about "HIV Fusion Inhibitors" by people in this website by year, and whether "HIV Fusion Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 2 | 3 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 10 | 0 | 10 |
| 2018 | 6 | 0 | 6 |
| 2019 | 6 | 1 | 7 |
| 2021 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "HIV Fusion Inhibitors" by people in Profiles.
-
Pan-coronavirus fusion inhibitors possess potent inhibitory activity against HIV-1, HIV-2, and simian immunodeficiency virus. Emerg Microbes Infect. 2021 Dec; 10(1):810-821.
-
Lipopeptide-based pan-CoV fusion inhibitors potently inhibit HIV-1 infection. Microbes Infect. 2021 Sep-Oct; 23(8):104840.
-
Design and Biological Evaluation of m-Xylene Thioether-Stapled Short Helical Peptides Targeting the HIV-1 gp41 Hexameric Coiled-Coil Fusion Complex. J Med Chem. 2019 10 10; 62(19):8773-8783.
-
Long-Acting HIV-1 Fusion Inhibitory Peptides and their Mechanisms of Action. Viruses. 2019 09 02; 11(9).
-
Development of Protein- and Peptide-Based HIV Entry Inhibitors Targeting gp120 or gp41. Viruses. 2019 08 01; 11(8).
-
Massively Parallel Profiling of HIV-1 Resistance to the Fusion Inhibitor Enfuvirtide. Viruses. 2019 05 15; 11(5).
-
A Peptide-Based HIV-1 Fusion Inhibitor with Two Tail-Anchors and Palmitic Acid Exhibits Substantially Improved In Vitro and Ex Vivo Anti-HIV-1 Activity and Prolonged In Vivo Half-Life. Molecules. 2019 Mar 21; 24(6).
-
Unexpected drug emerges for stroke recovery. Science. 2019 02 22; 363(6429):805.
-
Investigational drugs in HIV: Pros and cons of entry and fusion inhibitors (Review). Mol Med Rep. 2019 Mar; 19(3):1987-1995.
-
Reduced Susceptibility to VIRIP-Based HIV-1 Entry Inhibitors Has a High Genetic Barrier and Severe Fitness Costs. J Virol. 2018 09 01; 92(17).