"Sporozoites" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The product of meiotic division of zygotes in parasitic protozoa comprising haploid cells. These infective cells invade the host and undergo asexual reproduction producing MEROZOITES (or other forms) and ultimately gametocytes.
| Descriptor ID |
D034101
|
| MeSH Number(s) |
A11.870.740.600.800 B05.500.675.800 B05.775.740.600.800 G07.345.500.550.500.675.800
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Sporozoites".
Below are MeSH descriptors whose meaning is more specific than "Sporozoites".
This graph shows the total number of publications written about "Sporozoites" by people in this website by year, and whether "Sporozoites" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2017 | 1 | 7 | 8 |
| 2018 | 2 | 1 | 3 |
| 2019 | 2 | 1 | 3 |
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Below are the most recent publications written about "Sporozoites" by people in Profiles.
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Irradiated sporozoite vaccination induces sex-specific immune responses and protection against malaria in mice. Vaccine. 2019 07 26; 37(32):4468-4476.
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Vaccination With Sporozoites: Models and Correlates of Protection. Front Immunol. 2019; 10:1227.
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Hepatic spheroids used as an in vitro model to study malaria relapse. Biomaterials. 2019 09; 216:119221.
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Baculovirus-Induced Fast-Acting Innate Immunity Kills Liver-Stage Plasmodium. J Immunol. 2018 10 15; 201(8):2441-2451.
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A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection. Cell Rep. 2018 03 13; 22(11):2951-2963.
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Adenovirus-prime and baculovirus-boost heterologous immunization achieves sterile protection against malaria sporozoite challenge in a murine model. Sci Rep. 2018 03 01; 8(1):3896.
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The frontline of controlled human malaria infections: A report from the controlled human infection models Workshop in Leiden University Medical Centre 5 May 2016. Vaccine. 2017 12 18; 35(51):7065-7069.
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Novel Plasmodium antigens identified via genome-based antibody screen induce protection associated with polyfunctional T cell responses. Sci Rep. 2017 11 08; 7(1):15053.
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Modest heterologous protection after Plasmodium falciparum sporozoite immunization: a double-blind randomized controlled clinical trial. BMC Med. 2017 09 13; 15(1):168.
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DSM265 for Plasmodium falciparum chemoprophylaxis: a randomised, double blinded, phase 1 trial with controlled human malaria infection. Lancet Infect Dis. 2017 06; 17(6):636-644.