"Neuropilin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dimeric cell surface receptor involved in angiogenesis (NEOVASCULARIZATION, PHYSIOLOGICAL) and AXONAL GUIDANCE. Neuropilin-1 is a 140-kDa transmembrane protein that binds CLASS 3 SEMAPHORINS, and several other growth factors. Neuropilin-1 forms complexes with plexins or VEGF RECEPTORS; their binding affinity and specificity are determined by the composition of the neuropilin dimer and the identity of other receptors complexed with it. Neuropilin-1 is expressed in distinct patterns during neural development, complementary to those described for NEUROPILIN-2.
Descriptor ID |
D039942
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MeSH Number(s) |
D12.776.543.750.590.500
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Concept/Terms |
Neuropilin-1- Neuropilin-1
- Neuropilin 1
- Sema III Receptor
- Receptor, Sema III
- NRP1 Protein
- Semaphorin III Receptor
- A5 Antigen
- Antigen, A5
- Npn-1 Protein
- Npn 1 Protein
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Below are MeSH descriptors whose meaning is more general than "Neuropilin-1".
Below are MeSH descriptors whose meaning is more specific than "Neuropilin-1".
This graph shows the total number of publications written about "Neuropilin-1" by people in this website by year, and whether "Neuropilin-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2017 | 2 | 0 | 2 |
2018 | 2 | 2 | 4 |
2019 | 4 | 0 | 4 |
2020 | 4 | 0 | 4 |
2021 | 3 | 6 | 9 |
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Below are the most recent publications written about "Neuropilin-1" by people in Profiles.
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Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate. Emerg Microbes Infect. 2021 Dec; 10(1):1065-1076.
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Differential plasmacytoid dendritic cell phenotype and type I Interferon response in asymptomatic and severe COVID-19 infection. PLoS Pathog. 2021 09; 17(9):e1009878.
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Exploring Koch's postulate for SARS-CoV-2-induced acute pancreatitis: is it all about the ACE? Br J Surg. 2021 08 19; 108(8):879-881.
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SARS-CoV-2 pseudovirus infectivity and expression of viral entry-related factors ACE2, TMPRSS2, Kim-1, and NRP-1 in human cells from the respiratory, urinary, digestive, reproductive, and immune systems. J Med Virol. 2021 12; 93(12):6671-6685.
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Diabetic Nephropathy and COVID-19: The Potential Role of Immune Actors. Int J Mol Sci. 2021 Jul 21; 22(15).
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Fox3+ CD25+ CD4+ T-regulatory cells may transform the nCoV's final destiny to CNS! J Med Virol. 2021 10; 93(10):5673-5675.
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Triangle of cytokine storm, central nervous system involvement, and viral infection in COVID-19: the role of sFasL and neuropilin-1. Rev Neurosci. 2022 02 23; 33(2):147-160.
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Environmentally-induced mdig contributes to the severity of COVID-19 through fostering expression of SARS-CoV-2 receptor NRPs and glycan metabolism. Theranostics. 2021; 11(16):7970-7983.
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Neuropilin-1: A feasible link between liver pathologies and COVID-19. World J Gastroenterol. 2021 Jun 28; 27(24):3516-3529.
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In silico analysis identifies neuropilin-1 as a potential therapeutic target for SARS-Cov-2 infected lung cancer patients. Aging (Albany NY). 2021 06 24; 13(12):15770-15784.