"Acid Ceramidase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ceramidase subtype that is active at acid pH. It plays an important role in sphingolipid degradation by catalyzing the lysosomal hydrolysis of ceramide to sphingosine and free fatty acid. Inherited deficiency of acid ceramidase activity results in FARBER LIPOGRANULOMATOSIS.
Descriptor ID |
D055573
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MeSH Number(s) |
D08.811.277.087.250.100
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Acid Ceramidase".
Below are MeSH descriptors whose meaning is more specific than "Acid Ceramidase".
This graph shows the total number of publications written about "Acid Ceramidase" by people in this website by year, and whether "Acid Ceramidase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2016 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Acid Ceramidase" by people in Profiles.
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Alterations of lipid metabolism provide serologic biomarkers for the detection of asymptomatic versus symptomatic COVID-19 patients. Sci Rep. 2021 07 09; 11(1):14232.
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Molecular Mechanism of Inhibition of Acid Ceramidase by Carmofur. J Med Chem. 2019 01 24; 62(2):987-992.
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Chronic lung injury and impaired pulmonary function in a mouse model of acid ceramidase deficiency. Am J Physiol Lung Cell Mol Physiol. 2018 03 01; 314(3):L406-L420.
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ASAH1 variant causing a mild SMA phenotype with no myoclonic epilepsy: a clinical, biochemical and molecular study. Eur J Hum Genet. 2016 11; 24(11):1578-1583.