"Lopinavir" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An HIV protease inhibitor used in a fixed-dose combination with RITONAVIR. It is also an inhibitor of CYTOCHROME P-450 CYP3A.
Descriptor ID |
D061466
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MeSH Number(s) |
D03.383.742.698.553
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Concept/Terms |
Lopinavir- Lopinavir
- N-(4-(((2,6-dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pydrimidineacetamide
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Below are MeSH descriptors whose meaning is more general than "Lopinavir".
Below are MeSH descriptors whose meaning is more specific than "Lopinavir".
This graph shows the total number of publications written about "Lopinavir" by people in this website by year, and whether "Lopinavir" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2004 | 0 | 4 | 4 |
2005 | 0 | 1 | 1 |
2006 | 0 | 2 | 2 |
2009 | 0 | 1 | 1 |
2012 | 2 | 0 | 2 |
2013 | 1 | 1 | 2 |
2014 | 0 | 4 | 4 |
2015 | 1 | 1 | 2 |
2016 | 1 | 3 | 4 |
2017 | 2 | 7 | 9 |
2018 | 6 | 8 | 14 |
2019 | 0 | 1 | 1 |
2020 | 67 | 105 | 172 |
2021 | 12 | 36 | 48 |
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Below are the most recent publications written about "Lopinavir" by people in Profiles.
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Synthetic Attempts Towards Eminent Anti-viral Candidates of SARS-CoV. Mini Rev Med Chem. 2022; 22(2):232-247.
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How trustworthy guidelines can impact outcomes. Curr Opin Crit Care. 2021 10 01; 27(5):544-550.
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COVID-19: potential therapeutics for pediatric patients. Pharmacol Rep. 2021 Dec; 73(6):1520-1538.
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Comparative therapeutic efficacy of interferon alfa-2b and combination lopinavir/ritonavir plus interferon alfa-2b against SARS-CoV-2. BMC Infect Dis. 2021 Aug 30; 21(1):885.
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The comparison of favipiravir and lopinavir/ritonavir combination in COVID-19 treatment Turk J Med Sci. 2021 08 30; 51(4):1624-1630.
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Risk factors for prolonged virus shedding of respiratory tract and fecal in adults with severe acute respiratory syndrome coronavirus-2 infection. J Clin Lab Anal. 2021 Sep; 35(9):e23923.
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Current evidence for the risk of PR prolongation, QRS widening, QT prolongation, from lopinavir, ritonavir, atazanavir, and saquinavir: A systematic review. Medicine (Baltimore). 2021 Aug 06; 100(31):e26787.
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Drug-induced liver injury associated with lopinavir-ritonavir in patients with COVID-19: a disproportionality analysis of U.S. food and drug administration adverse event reporting system (FAERS) data. Int J Clin Pharm. 2021 Aug; 43(4):1116-1122.
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Comparing the effectiveness of Atazanavir/Ritonavir/Dolutegravir/Hydroxychloroquine and Lopinavir/Ritonavir/Hydroxychloroquine treatment regimens in COVID-19 patients. J Med Virol. 2021 12; 93(12):6557-6565.
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Characteristics, clinical outcomes, and risk factors of SARS-COV-2 infection in adult acute myeloid leukemia patients: experience of the PETHEMA group. Leuk Lymphoma. 2021 12; 62(12):2928-2938.