Receptor, Metabotropic Glutamate 5
"Receptor, Metabotropic Glutamate 5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type I G protein-coupled receptor mostly expressed post-synaptic pyramidal cells of the cortex and CENTRAL NERVOUS SYSTEM.
| Descriptor ID |
D064529
|
| MeSH Number(s) |
D12.776.543.750.695.450.500 D12.776.543.750.720.200.450.500.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Metabotropic Glutamate 5".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Metabotropic Glutamate [D12.776.543.750.695.450]
- Receptor, Metabotropic Glutamate 5 [D12.776.543.750.695.450.500]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Amino Acid [D12.776.543.750.720.200]
- Receptors, Glutamate [D12.776.543.750.720.200.450]
- Receptors, Metabotropic Glutamate [D12.776.543.750.720.200.450.500]
- Receptor, Metabotropic Glutamate 5 [D12.776.543.750.720.200.450.500.500]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Metabotropic Glutamate 5".
This graph shows the total number of publications written about "Receptor, Metabotropic Glutamate 5" by people in this website by year, and whether "Receptor, Metabotropic Glutamate 5" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
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Below are the most recent publications written about "Receptor, Metabotropic Glutamate 5" by people in Profiles.
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E-pharmacophore-based screening of mGluR5 negative allosteric modulators for central nervous system disorder. Comput Biol Chem. 2019 Feb; 78:414-423.
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Atom-based 3D-QSAR, induced fit docking, and molecular dynamics simulations study of thieno[2,3-b]pyridines negative allosteric modulators of mGluR5. J Recept Signal Transduct Res. 2018 Jun; 38(3):225-239.
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Altered metabotropic glutamate receptor 5 markers in PTSD: In vivo and postmortem evidence. Proc Natl Acad Sci U S A. 2017 08 01; 114(31):8390-8395.