"Vaccines, Attenuated" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Live vaccines prepared from microorganisms which have undergone physical adaptation (e.g., by radiation or temperature conditioning) or serial passage in laboratory animal hosts or infected tissue/cell cultures, in order to produce avirulent mutant strains capable of inducing protective immunity.
| Descriptor ID |
D014613
|
| MeSH Number(s) |
D20.215.894.811
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Vaccines, Attenuated".
Below are MeSH descriptors whose meaning is more specific than "Vaccines, Attenuated".
This graph shows the total number of publications written about "Vaccines, Attenuated" by people in this website by year, and whether "Vaccines, Attenuated" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2002 | 0 | 3 | 3 |
| 2004 | 0 | 5 | 5 |
| 2005 | 0 | 2 | 2 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 1 | 2 | 3 |
| 2010 | 2 | 1 | 3 |
| 2011 | 0 | 4 | 4 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 3 | 3 |
| 2015 | 0 | 5 | 5 |
| 2016 | 1 | 4 | 5 |
| 2017 | 13 | 54 | 67 |
| 2018 | 26 | 47 | 73 |
| 2019 | 8 | 23 | 31 |
| 2020 | 4 | 11 | 15 |
| 2021 | 1 | 7 | 8 |
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Below are the most recent publications written about "Vaccines, Attenuated" by people in Profiles.
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Live attenuated coronavirus vaccines deficient in N7-Methyltransferase activity induce both humoral and cellular immune responses in mice. Emerg Microbes Infect. 2021 Dec; 10(1):1626-1637.
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SARS-CoV-2 Bearing a Mutation at the S1/S2 Cleavage Site Exhibits Attenuated Virulence and Confers Protective Immunity. mBio. 2021 08 31; 12(4):e0141521.
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Could live attenuated vaccines better control COVID-19? Vaccine. 2021 09 15; 39(39):5719-5726.
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Sars-Cov-2 virus and vaccination; biological and statistical framework. Expert Rev Vaccines. 2021 09; 20(9):1059-1063.
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Contribution of SARS-CoV-2 Accessory Proteins to Viral Pathogenicity in K18 Human ACE2 Transgenic Mice. J Virol. 2021 08 10; 95(17):e0040221.
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Repurposing of the childhood vaccines: could we train the immune system against the SARS-CoV-2. Expert Rev Vaccines. 2021 09; 20(9):1051-1057.
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Are We Paving the Way to Dig Out of the "Pandemic Hole"? A Narrative Review on SARS-CoV-2 Vaccination: From Animal Models to Human Immunization. Med Sci (Basel). 2021 07 30; 9(3).
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Scalable live-attenuated SARS-CoV-2 vaccine candidate demonstrates preclinical safety and efficacy. Proc Natl Acad Sci U S A. 2021 07 20; 118(29).
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Development of safe and highly protective live-attenuated SARS-CoV-2 vaccine candidates by genome recoding. Cell Rep. 2021 08 03; 36(5):109493.
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Replication and vaccine protection of multiple infectious bronchitis virus strains in pheasants (Phasianus colchicus). Infect Genet Evol. 2021 09; 93:104980.