"Receptors, LDL" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Receptors on the plasma membrane of nonhepatic cells that specifically bind LDL. The receptors are localized in specialized regions called coated pits. Hypercholesteremia is caused by an allelic genetic defect of three types: 1, receptors do not bind to LDL; 2, there is reduced binding of LDL; and 3, there is normal binding but no internalization of LDL. In consequence, entry of cholesterol esters into the cell is impaired and the intracellular feedback by cholesterol on 3-hydroxy-3-methylglutaryl CoA reductase is lacking.
| Descriptor ID |
D011973
|
| MeSH Number(s) |
D12.776.543.750.710.450
|
| Concept/Terms |
Receptors, LDL- Receptors, LDL
- LDL Receptors
- LDL Receptors, Lipoprotein
- Receptors, Lipoprotein LDL
- Lipoprotein LDL Receptors
- Low Density Lipoprotein Receptors
- Receptors, Lipoprotein, LDL
- Receptors, Low Density Lipoprotein
- LDL Receptor
- Receptor, LDL
- Low Density Lipoprotein Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptors, LDL".
Below are MeSH descriptors whose meaning is more specific than "Receptors, LDL".
This graph shows the total number of publications written about "Receptors, LDL" by people in this website by year, and whether "Receptors, LDL" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2017 | 5 | 9 | 14 |
| 2018 | 5 | 6 | 11 |
| 2019 | 0 | 2 | 2 |
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Below are the most recent publications written about "Receptors, LDL" by people in Profiles.
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Why the lower reported prevalence of asthma in patients diagnosed with COVID-19 validates repurposing EDTA solutions to prevent and manage treat COVID-19 disease. Med Hypotheses. 2020 Nov; 144:110027.
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Effects of melatonin administration on mental health parameters, metabolic and genetic profiles in women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial. J Affect Disord. 2019 05 01; 250:51-56.
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Oxidized Low-Density Lipoprotein Receptor in Lymphocytes Prevents Atherosclerosis and Predicts Subclinical Disease. Circulation. 2019 01 08; 139(2):243-255.
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[Screening of LDLR gene mutations in nine patients with familial hypercholesterolemia]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2018 Dec 10; 35(6):783-786.
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Inhibiting PCSK9 - biology beyond LDL control. Nat Rev Endocrinol. 2018 12; 15(1):52-62.
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PCSK9 expression in the ischaemic heart and its relationship to infarct size, cardiac function, and development of autophagy. Cardiovasc Res. 2018 11 01; 114(13):1738-1751.
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Predominant Role of Nuclear Versus Membrane Estrogen Receptor a in Arterial Protection: Implications for Estrogen Receptor a Modulation in Cardiovascular Prevention/Safety. J Am Heart Assoc. 2018 06 29; 7(13).
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Case report-Rapid regression of xanthomas under lipoprotein apheresis in a boy with homozygous familial hypercholesterolemia. J Clin Lipidol. 2018 Jul - Aug; 12(4):868-871.
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Anionic nanoliposomes reduced atherosclerosis progression in Low Density Lipoprotein Receptor (LDLR) deficient mice fed a high fat diet. J Cell Physiol. 2018 10; 233(10):6951-6964.
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Molecular aspects of hypercholesterolemia treatment: current perspectives and hopes. Ann Med. 2018 06; 50(4):303-311.