Polyendocrinopathies, Autoimmune
"Polyendocrinopathies, Autoimmune" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Autoimmune diseases affecting multiple endocrine organs. Type I is characterized by childhood onset and chronic mucocutaneous candidiasis (CANDIDIASIS, CHRONIC MUCOCUTANEOUS), while type II exhibits any combination of adrenal insufficiency (ADDISON'S DISEASE), lymphocytic thyroiditis (THYROIDITIS, AUTOIMMUNE;), HYPOPARATHYROIDISM; and gonadal failure. In both types organ-specific ANTIBODIES against a variety of ENDOCRINE GLANDS have been detected. The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.
| Descriptor ID |
D016884
|
| MeSH Number(s) |
C19.787 C20.111.750
|
| Concept/Terms |
Polyglandular Type III Autoimmune Syndrome- Polyglandular Type III Autoimmune Syndrome
- Polyglandular Autoimmune Syndrome, Type 3
- Autoimmune Syndrome Type III, Polyglandular
- Autoimmune Polyglandular Syndrome Type III
- Autoimmune Polyglandular Syndrome, Type 3
Polyglandular Type I Autoimmune Syndrome- Polyglandular Type I Autoimmune Syndrome
- APECED
- APS Type 1
- Autoimmune Polyendocrinopathy Syndrome Type 1
- Autoimmune Polyendocrinopathy with Candidiasis and Ectodermal Dystrophy
- Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy
- Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy
- Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy, Autoimmune
- Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy
- Autoimmune Polyglandular Syndrome Type I
- Autoimmune Polyglandular Syndrome, Type 1
- Autoimmune Polyglandular Syndrome, Type I
- Autoimmune Syndrome Type I, Polyglandular
- Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy, Autoimmune
- Polyendocrinopathy Candidiasis Ectodermal Dystrophy, Autoimmune
- Polyglandular Autoimmune Syndrome, Type 1
- Polyglandular Autoimmune Syndrome, Type I
- AIRE Deficiency
- AIRE Deficiencies
- Deficiency, AIRE
Polyglandular Type II Autoimmune Syndrome- Polyglandular Type II Autoimmune Syndrome
- Autoimmune Polyendocrine Syndrome, Type II
- Autoimmune Polyglandular Syndrome Type II
- Autoimmune Syndrome Type II, Polyglandular
- Diabetes Mellitus, Addison Disease, Myxedema
- Schmidt's Syndrome
- Syndrome, Schmidt's
- Multiple Endocrine Deficiency Syndrome, Type 2
- Polyendocrine Autoimmune Syndrome, Type II
- Polyglandular Autoimmune Syndrome, Type 2
- Polyglandular Deficiency Syndrome, Type 2
- Schmidt Syndrome
- Syndrome, Schmidt
- Autoimmune Polyendocrine Syndrome, Type 2
- Diabetes Mellitus, Addison's Disease, Myxedema
|
Below are MeSH descriptors whose meaning is more general than "Polyendocrinopathies, Autoimmune".
Below are MeSH descriptors whose meaning is more specific than "Polyendocrinopathies, Autoimmune".
This graph shows the total number of publications written about "Polyendocrinopathies, Autoimmune" by people in this website by year, and whether "Polyendocrinopathies, Autoimmune" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2017 | 4 | 0 | 4 |
| 2018 | 2 | 1 | 3 |
| 2019 | 3 | 0 | 3 |
| 2020 | 1 | 0 | 1 |
| 2021 | 4 | 0 | 4 |
To return to the timeline, click here.
Below are the most recent publications written about "Polyendocrinopathies, Autoimmune" by people in Profiles.
-
Infections in the monogenic autoimmune syndrome APECED. Curr Opin Immunol. 2021 10; 72:286-297.
-
Mild COVID-19 despite autoantibodies against type I IFNs in autoimmune polyendocrine syndrome type 1. J Clin Invest. 2021 07 15; 131(14).
-
Preexisting autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-1. J Exp Med. 2021 07 05; 218(7).
-
Severe COVID-19 in an APS1 patient with interferon autoantibodies treated with plasmapheresis. J Allergy Clin Immunol. 2021 07; 148(1):96-98.
-
Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy in Two Siblings: Same Mutations but Very Different Phenotypes. Genes (Basel). 2021 01 26; 12(2).
-
A COVID-19 pneumonia case report of autoimmune polyendocrine syndrome type 1 in Lombardy, Italy: letter to the editor. J Endocrinol Invest. 2020 Aug; 43(8):1175-1177.
-
AIRE expression controls the peripheral selection of autoreactive B cells. Sci Immunol. 2019 04 12; 4(34).
-
Jaundice and anaemia as presenting features of an incomplete autoimmune polyglandular syndrome type II. BMJ Case Rep. 2019 Apr 08; 12(4).
-
Reduction of Total Brain and Cerebellum Volumes Associated With Neuronal Autoantibodies in Patients With APECED. J Clin Endocrinol Metab. 2019 01 01; 104(1):150-162.
-
Implications for screening in the hypothyroid presentation of autoimmune polyglandular syndrome. Eur J Intern Med. 2019 01; 59:e23-e24.