DNA Modification Methylases
"DNA Modification Methylases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that are part of the restriction-modification systems. They are responsible for producing a species-characteristic methylation pattern, on either adenine or cytosine residues, in a specific short base sequence in the host cell's own DNA. This methylated sequence will occur many times in the host-cell DNA and remain intact for the lifetime of the cell. Any DNA from another species which gains entry into a living cell and lacks the characteristic methylation pattern will be recognized by the restriction endonucleases of similar specificity and destroyed by cleavage. Most have been studied in bacterial systems, but a few have been found in eukaryotic organisms.
Descriptor ID |
D015254
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MeSH Number(s) |
D08.811.150.240 D08.811.913.555.500.350
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Concept/Terms |
DNA Modification Methylases- DNA Modification Methylases
- Methylases, DNA Modification
- Modification Methylases, DNA
- Modification Methylases
- Methylases, Modification
- DNA Modification Methyltransferases
- Methyltransferases, DNA Modification
- Modification Methyltransferases, DNA
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Below are MeSH descriptors whose meaning is more general than "DNA Modification Methylases".
Below are MeSH descriptors whose meaning is more specific than "DNA Modification Methylases".
This graph shows the total number of publications written about "DNA Modification Methylases" by people in this website by year, and whether "DNA Modification Methylases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2016 | 0 | 1 | 1 |
2017 | 3 | 1 | 4 |
2018 | 3 | 1 | 4 |
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Below are the most recent publications written about "DNA Modification Methylases" by people in Profiles.
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The Role of Temozolomide in Patients With Newly Diagnosed Wild-Type IDH, Unmethylated MGMTp Glioblastoma During the COVID-19 Pandemic. JAMA Oncol. 2021 05 01; 7(5):675-676.
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Targeting epigenetic DNA and histone modifications to treat kidney disease. Nephrol Dial Transplant. 2018 11 01; 33(11):1875-1886.
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Bio-analytical applications of nicking endonucleases assisted signal-amplification strategies for detection of cancer biomarkers -DNA methyl transferase and microRNA. Biosens Bioelectron. 2019 Jan 15; 124-125:233-243.
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Deep-Learning Convolutional Neural Networks Accurately Classify Genetic Mutations in Gliomas. AJNR Am J Neuroradiol. 2018 07; 39(7):1201-1207.
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Limited Role of Promoter Methylation of MGMT and C13ORF18 in Triage of Low-Grade Squamous Intraepithelial Lesion. Chin Med J (Engl). 2018 Apr 20; 131(8):939-944.
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Phasevarion-Regulated Virulence in the Emerging Pediatric Pathogen Kingella kingae. Infect Immun. 2017 12; 85(12).
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Host Methyltransferases and Demethylases: Potential New Epigenetic Targets for HIV Cure Strategies and Beyond. AIDS Res Hum Retroviruses. 2017 Nov; 33(S1):S8-S22.
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[Effects of Traffic-related Air Pollution Exposure on DNA Methylation]. Huan Jing Ke Xue. 2017 Aug 08; 38(8):3529-3535.
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Influence of MTHFR Genetic Background on p16 and MGMT Methylation in Oral Squamous Cell Cancer. Int J Mol Sci. 2017 Mar 29; 18(4).
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Pathological characterization of nivolumab-related liver injury in a patient with glioblastoma. Immunotherapy. 2016 12; 8(12):1363-1369.