"HIV Integrase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzyme of the HUMAN IMMUNODEFICIENCY VIRUS that is required to integrate viral DNA into cellular DNA in the nucleus of a host cell. HIV integrase is a DNA nucleotidyltransferase encoded by the pol gene.
| Descriptor ID |
D019427
|
| MeSH Number(s) |
D08.811.739.500.667.500 D08.811.913.696.445.825.500 D12.776.964.775.375.545.500 D12.776.964.775.562.764.500 D12.776.964.970.600.850.375.545.500
|
| Concept/Terms |
HIV Integrase- HIV Integrase
- Integrase, HIV
- p31 pol Gene Product, Human Immunodeficiency Virus
- p31 Integrase Protein, Human Immunodeficiency Virus
- p31 pol Gene Product, HIV
- HIV Integration Protein
- Integration Protein, HIV
- p31 Integrase Protein, HIV
|
Below are MeSH descriptors whose meaning is more general than "HIV Integrase".
Below are MeSH descriptors whose meaning is more specific than "HIV Integrase".
This graph shows the total number of publications written about "HIV Integrase" by people in this website by year, and whether "HIV Integrase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 2 | 1 | 3 |
| 2017 | 8 | 6 | 14 |
| 2018 | 5 | 6 | 11 |
| 2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "HIV Integrase" by people in Profiles.
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Ivermectin as a Broad-Spectrum Host-Directed Antiviral: The Real Deal? Cells. 2020 09 15; 9(9).
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A viral genome wide association study and genotypic resistance testing in patients failing first line antiretroviral therapy in the first large countrywide Ethiopian HIV cohort. BMC Infect Dis. 2019 Jul 01; 19(1):569.
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Integrase strand transfer inhibitor-based regimen is related with a limited HIV-1 V3 loop evolution in clinical practice. Virus Genes. 2019 Jun; 55(3):290-297.
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The S230R Integrase Substitution Associated With Virus Load Rebound During Dolutegravir Monotherapy Confers Low-Level Resistance to Integrase Strand-Transfer Inhibitors. J Infect Dis. 2018 07 24; 218(5):698-706.
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Evaluation of different analysis pipelines for the detection of HIV-1 minority resistant variants. PLoS One. 2018; 13(6):e0198334.
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Comparison of an In Vitro Diagnostic Next-Generation Sequencing Assay with Sanger Sequencing for HIV-1 Genotypic Resistance Testing. J Clin Microbiol. 2018 06; 56(6).
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Integrase Strand Transfer Inhibitor Resistance Mutations in Antiretroviral Treatment-naïve Patients in Korea: a Prospective, Observational Study. J Korean Med Sci. 2018 Jun 18; 33(25):e173.
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Prevalence of Integrase Strand Transfer Inhibitors Resistance Mutations in Integrase Strand Transfer Inhibitors-Naive and -Experienced HIV-1 Infected Patients: A Single Center Experience. AIDS Res Hum Retroviruses. 2018 07; 34(7):570-574.
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Pathway involving the N155H mutation in HIV-1 integrase leads to dolutegravir resistance. J Antimicrob Chemother. 2018 05 01; 73(5):1158-1166.
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Phenotypic analysis of HIV-1 E157Q integrase polymorphism and impact on virological outcome in patients initiating an integrase inhibitor-based regimen. J Antimicrob Chemother. 2018 04 01; 73(4):1039-1044.