"Genistein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An isoflavonoid derived from soy products. It inhibits PROTEIN-TYROSINE KINASE and topoisomerase-II (DNA TOPOISOMERASES, TYPE II); activity and is used as an antineoplastic and antitumor agent. Experimentally, it has been shown to induce G2 PHASE arrest in human and murine cell lines and inhibits PROTEIN-TYROSINE KINASE.
| Descriptor ID |
D019833
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| MeSH Number(s) |
D03.383.663.283.266.450.400.375 D03.633.100.150.266.450.400.375
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Genistein".
Below are MeSH descriptors whose meaning is more specific than "Genistein".
This graph shows the total number of publications written about "Genistein" by people in this website by year, and whether "Genistein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 3 | 1 | 4 |
| 2018 | 5 | 2 | 7 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Genistein" by people in Profiles.
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Identification of COVID-19 and Dengue Host Factor Interaction Networks Based on Integrative Bioinformatics Analyses. Front Immunol. 2021; 12:707287.
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Supplementing Genistein for Breeder Hens Alters the Fatty Acid Metabolism and Growth Performance of Offsprings by Epigenetic Modification. Oxid Med Cell Longev. 2019; 2019:9214209.
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Anti-oxidative effects of 17 ß-estradiol and genistein in human skin fibroblasts and keratinocytes. J Dermatol Sci. 2018 Oct; 92(1):62-77.
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Genistein Enhances or Reduces Glycosaminoglycan Quantity in a Cell Type-Specific Manner. Cell Physiol Biochem. 2018; 47(4):1667-1681.
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Linoleic Acid Attenuates the Toxic Dose of Bupivacaine-Mediated Reduction of Vasodilation Evoked by the Activation of Adenosine Triphosphate-Sensitive Potassium Channels. Int J Mol Sci. 2018 Jun 26; 19(7).
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Genistein Ameliorates Non-alcoholic Fatty Liver Disease by Targeting the Thromboxane A2 Pathway. J Agric Food Chem. 2018 Jun 13; 66(23):5853-5859.
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In silico estrogen-like activity and in vivo osteoclastogenesis inhibitory effect of Cicer arietinum extract. Cell Mol Biol (Noisy-le-grand). 2018 Apr 30; 64(5):29-39.
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Dietary genistein supplementation for breeders and their offspring improves the growth performance and immune function of broilers. Sci Rep. 2018 03 26; 8(1):5161.
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Dietary genistein supplementation in laying broiler breeder hens alters the development and metabolism of offspring embryos as revealed by hepatic transcriptome analysis. FASEB J. 2018 08; 32(8):4214-4228.
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Modulation of Oxidative Stress by 17 ß-Estradiol and Genistein in Human Hepatic Cell Lines In Vitro. Cell Physiol Biochem. 2017; 42(3):1051-1062.