"Thiazolidinediones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
THIAZOLES with two keto oxygens. Members are insulin-sensitizing agents which overcome INSULIN RESISTANCE by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma).
Descriptor ID |
D045162
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MeSH Number(s) |
D02.886.675.933 D03.383.129.708.933
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Thiazolidinediones".
Below are MeSH descriptors whose meaning is more specific than "Thiazolidinediones".
This graph shows the total number of publications written about "Thiazolidinediones" by people in this website by year, and whether "Thiazolidinediones" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2007 | 1 | 0 | 1 |
2009 | 0 | 2 | 2 |
2012 | 1 | 1 | 2 |
2013 | 0 | 1 | 1 |
2014 | 1 | 1 | 2 |
2015 | 1 | 0 | 1 |
2017 | 10 | 6 | 16 |
2018 | 2 | 3 | 5 |
2019 | 2 | 2 | 4 |
2020 | 0 | 2 | 2 |
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Below are the most recent publications written about "Thiazolidinediones" by people in Profiles.
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Higher ACE2 expression levels in epicardial cells than subcutaneous stromal cells from patients with cardiovascular disease: Diabetes and obesity as possible enhancer. Eur J Clin Invest. 2021 May; 51(5):e13463.
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Pharmacotherapeutic considerations for the management of diabetes mellitus among hospitalized COVID-19 patients. Expert Opin Pharmacother. 2021 Feb; 22(2):229-240.
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Currently prescribed drugs in the UK that could upregulate or downregulate ACE2 in COVID-19 disease: a systematic review. BMJ Open. 2020 09 14; 10(9):e040644.
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Dissecting the interaction between COVID-19 and diabetes mellitus. J Diabetes Investig. 2020 Sep; 11(5):1104-1114.
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Pharmacological (or Synthetic) and Nutritional Agonists of PPAR-? as Candidates for Cytokine Storm Modulation in COVID-19 Disease. Molecules. 2020 Apr 29; 25(9).
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Can pioglitazone be potentially useful therapeutically in treating patients with COVID-19? Med Hypotheses. 2020 Jul; 140:109776.
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Insight of the Interaction between 2,4-thiazolidinedione and Human Serum Albumin: A Spectroscopic, Thermodynamic and Molecular Docking Study. Int J Mol Sci. 2019 Jun 03; 20(11).
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Overexpression of tensin homolog deleted on chromosome ten (PTEN) by ciglitazone sensitizes doxorubicin-resistance leukemia cancer cells to treatment. J Cell Biochem. 2019 09; 120(9):15719-15729.
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Long-term effect of pioglitazone vs glimepiride on lipoprotein oxidation in patients with type 2 diabetes: a prospective randomized study. Acta Diabetol. 2019 May; 56(5):505-513.
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Personalizing metabolic disease therapies. Nat Med. 2019 02; 25(2):197.